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- Title
SSRIs vs. SNRIs for anxiety and OCD.
- Authors
Knopf, Alison
- Abstract
Selective serotonin reuptake inhibitors (SSRIs) have greater adverse event (AE)–related discontinuation of treatment than serotonin‐norepinephrine reuptake inhibitors (SNRIs) in the treatment of pediatric obsessive‐compulsive disorder (OCD) and anxiety disorders. And SSRIs are more likely than SNRIs to produce "activation" (restlessness). They're better than SNRIs for anxiety, but for youths who are activated by SSRIs, clinicians should consider SNRIs, which have a lower risk of activation, researchers have found in a meta‐analysis published in the Journal of the American Academy of Child and Adolescent Psychiatry.
- Subjects
DIARRHEA; HEADACHE risk factors; INSOMNIA risk factors; ABDOMINAL pain; ANESTHESIA; ANTIDEPRESSANTS; DRUG side effects; FLUOXETINE; INDIGESTION; NEUROTRANSMITTER uptake inhibitors; OBSESSIVE-compulsive disorder; SEROTONIN uptake inhibitors; SERTRALINE; SLEEP disorders; VENLAFAXINE; TERMINATION of treatment; ANXIETY disorders; TREATMENT effectiveness; SUICIDAL ideation; PAROXETINE; DULOXETINE; CITALOPRAM; FLUVOXAMINE; DISEASE risk factors
- Publication
Brown University Child & Adolescent Behavior Letter, 2020, Vol 36, Issue 3, p3
- ISSN
1058-1073
- Publication type
Article
- DOI
10.1002/cbl.30448