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- Title
A Rare Case Report of B-Cell Acute Lymphoblastic Leukemia with EP300::ZNF384 Fusion Gene.
- Authors
Xue Wu; Xiaofeng Yang; Yingying Chen; Zhihua Zhang; XinhongYang
- Abstract
This article, titled "A Rare Case Report of B-Cell Acute Lymphoblastic Leukemia with EP300::ZNF384 Fusion Gene," discusses a specific case of B-cell acute lymphoblastic leukemia (B-ALL) with a fusion gene called EP300::ZNF384. This fusion gene has been found in less than 60 reported cases and is associated with a favorable prognosis and good response to conventional chemotherapy. The article provides details about the patient's diagnosis, treatment, and genetic abnormalities, highlighting the importance of cytogenetic analysis in identifying such abnormalities. The study emphasizes the need for further research to classify and understand genetic lesions in B-ALL.
- Subjects
LYMPHOBLASTIC leukemia; ACUTE leukemia; GENE fusion; CELL fusion; ZINC-finger proteins
- Publication
Clinical Laboratory, 2024, Vol 70, Issue 6, p1232
- ISSN
1433-6510
- Publication type
Article
- DOI
10.7754/Clin.Lab.2023.231226