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- Title
The natural history of incidental retroperitoneal schwannomas.
- Authors
Ogose, Akira; Kawashima, Hiroyuki; Hatano, Hiroshi; Ariizumi, Takashi; Sasaki, Taro; Yamagishi, Tetsuro; Oike, Naoki; Inagawa, Syoichi; Endo, Naoto
- Abstract
The natural history of asymptomatic retroperitoneal schwannomas is poorly understood. This study aimed at investigating the natural history of incidental retroperitoneal schwannomas. The medical charts and imaging studies of 22 asymptomatic patients under observation for at least 12 months for retroperitoneal schwannomas were reviewed. The duration of follow-up ranged between 13 and 176 months (mean 48 months). In the 22 patients managed by the “wait and see” approach, the average tumor size at initial presentation was 51 mm, which increased to 57 mm at final follow-up. During the final follow-up, 2 patients required surgical treatment for tumor enlargement, while the remaining patients remained asymptomatic without surgery. The average growth rate of the tumors was 1.9 mm/year (range: -1.9 to 8.7 mm/year). The majority of asymptomatic retroperitoneal schwannomas demonstrate minimal growth and may be suitable for management with the “wait and see” approach.
- Subjects
NATURAL history; TUMOR growth; SCHWANNOMAS; DIAGNOSTIC imaging; LUMBAR pain
- Publication
PLoS ONE, 2019, Vol 14, Issue 4, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0215336