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- Title
The balance of acid, base and charge in health and disease.
- Authors
Cohen, Raphael M.; Feldman, George M.; Fernandez, Pedro C.
- Abstract
The term "homeostasis," has long been a favorite term of physiologists and clinicians interested in the role played by the kidneys in maintaining constant the body's internal milieu. In order to explain homeostasis, the concept of fluid, electrolyte and acid-base "balance" was developed. During the last thirty years, the understanding of the renal tubular, cellular and molecular mechanisms of urinary acidification has greatly broadened. In the present article, the factors involved in the day-to-day maintenance of acid-base balance will be reviewed first, integral. The oxidation of carbon containing fuels results in the over-whelming production of volatile acid in the form of carbon dioxide, ranging from 16,000 to 20,000 millimoles per day.
- Subjects
HOMEOSTASIS; PHYSIOLOGY; OXIDATION; CARBON dioxide; ACID-base equilibrium; ELECTROLYTES
- Publication
Kidney International, 1997, Vol 52, Issue 2, p287
- ISSN
0085-2538
- Publication type
Article
- DOI
10.1038/ki.1997.334