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- Title
Abstracts.
- Abstract
This article presents abstracts of various papers that were presented at the 48th Scientific Meeting of the Dutch Society of Nephrology that would be held on October 30, 1993. One of the papers discussed is "Renal Ischemia Contributes to Renal Damage in Rat Model of Antimyeloperoxidase Associated Necrotizing Crescentic Glomerulonephritis (NCGN)," by E. Brouwer, P.A. Klok, M.G. Huitema, J.J. Weening, and C.G.M. Kallenberg. Human anti-myeloperoxidase (MPO) associated NCGN is characterized by crescent formation and glomerular and interstitial infiltration with inflammatory cells. Focal fibrinoid necrosis of capillary loops is present at a very early stage in the development of NCGN, indicating that focal endothelial cell damage and GBM necrosis, possibly due to focal ischemia, are prerequisites for the development of NCGN in the presence of anti-MPO antibodies.
- Subjects
MEETINGS; KIDNEY diseases; ISCHEMIA; BLOOD circulation disorders; INTERNAL medicine; IMMUNOGLOBULINS; NECROSIS
- Publication
Kidney International, 1994, Vol 46, Issue 5, p1459
- ISSN
0085-2538
- Publication type
Abstract
- DOI
10.1111/1523-1755.ep14896091