We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Anodal cerebellar stimulation increases cortical activation: Evidence for cerebellar scaffolding of cortical processing.
- Authors
Maldonado, Ted; Jackson, Trevor Bryan; Bernard, Jessica A.
- Abstract
While the cerebellum contributes to nonmotor task performance, the specific contributions of the structure remain unknown. One possibility is that the cerebellum allows for the offloading of cortical processing, providing support during task performance, using internal models. Here we used transcranial direct current stimulation to modulate cerebellar function and investigate the impact on cortical activation patterns. Participants (n = 74; 22.03 ± 3.44 years) received either cathodal, anodal, or sham stimulation over the right cerebellum before a functional magnetic resonance imaging scan during which they completed a sequence learning and a working memory task. We predicted that cathodal stimulation would improve, and anodal stimulation would hinder task performance and cortical activation. Behaviorally, anodal stimulation negatively impacted behavior during late‐phase sequence learning. Functionally, we found that anodal cerebellar stimulation resulted in increased bilateral cortical activation, particularly in parietal and frontal regions known to be involved in cognitive processing. This suggests that if the cerebellum is not functioning optimally, there is a greater need for cortical resources.
- Subjects
TRANSCRANIAL direct current stimulation; FUNCTIONAL magnetic resonance imaging; PARIETAL lobe; TASK performance
- Publication
Human Brain Mapping, 2023, Vol 44, Issue 4, p1666
- ISSN
1065-9471
- Publication type
Article
- DOI
10.1002/hbm.26166