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- Title
Bioactivity Evaluation of Certain Hepatic Enzymes in Blood Plasma and Milk of Holstein Cows.
- Authors
Ping Liu; Bao Xiang He; Xian Ling Yang; Xiao Lu Hou; Jian Bin Han; Yin Hua Han; Pei Nie; Hui Fang Deng; Xiang Hong Du
- Abstract
Alanine aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyl-transferase (GGT), and alkaline phosphatase (ALP) are important catabolic enzymes, which play an important role in liver function of animals. The activities of these enzymes were monitored in milk and blood plasma and association between them was determined through regression analysis. Samples of milk and blood were collected from 35 housed multiparous Holstein cows 3-9 weeks postpartum. The results showed that there were significantly positive correlations for these four enzymes between the enzyme activities in milk and blood plasma (ALT, rs=0.852, P<0.001; AST, rs=0.341, P<0.001; GGT, rs=0.628, P<0.001; ALP, rs=0.707, P<0.001). Compared to the blood plasma, the activities of ALT (P<0.05) and AST (P<0.001) in milk appeared significantly lower, while the activities of GGT and ALP were significantly higher (P<0.001). With the regression models, it seems that detection of ALT, AST, GGT and ALP activities in milk may be an alternative way to monitor the liver function of cows. Therefore, this study is an initial step for studying the liver function through detection of these enzymes in milk.
- Subjects
BLOOD plasma; HOLSTEIN-Friesian cattle; BIOACTIVE compounds; ALANINE aminotransferase; ASPARTATE aminotransferase; ALKALINE phosphatase; ENZYME metabolism; MILK analysis
- Publication
Pakistan Veterinary Journal, 2012, Vol 32, Issue 4, p601
- ISSN
0253-8318
- Publication type
Article