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Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.
Published in:
Nature Medicine, 2012, v. 18, n. 3, p. 436, doi. 10.1038/nm.2610
By:
- Della Gatta, Giusy;
- Palomero, Teresa;
- Perez-Garcia, Arianne;
- Ambesi-Impiombato, Alberto;
- Bansal, Mukesh;
- Carpenter, Zachary W;
- De Keersmaecker, Kim;
- Sole, Xavier;
- Xu, Luyao;
- Paietta, Elisabeth;
- Racevskis, Janis;
- Wiernik, Peter H;
- Rowe, Jacob M;
- Meijerink, Jules P;
- Califano, Andrea;
- Ferrando, Adolfo A
Publication type:
Article
Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia.
Published in:
Nature Medicine, 2012, v. 18, n. 2, p. 298, doi. 10.1038/nm.2651
By:
- Ntziachristos, Panagiotis;
- Tsirigos, Aristotelis;
- Vlierberghe, Pieter Van;
- Nedjic, Jelena;
- Trimarchi, Thomas;
- Flaherty, Maria Sol;
- Ferres-Marco, Dolors;
- da Ros, Vanina;
- Tang, Zuojian;
- Siegle, Jasmin;
- Asp, Patrik;
- Hadler, Michael;
- Rigo, Isaura;
- Keersmaecker, Kim De;
- Patel, Jay;
- Huynh, Tien;
- Utro, Filippo;
- Poglio, Sandrine;
- Samon, Jeremy B;
- Paietta, Elisabeth
Publication type:
Article
The TLX1 oncogene drives aneuploidy in T cell transformation.
Published in:
Nature Medicine, 2010, v. 16, n. 11, p. 1321, doi. 10.1038/nm.2246
By:
- De Keersmaecker, Kim;
- Real, Pedro J.;
- Gatta, Giusy Della;
- Palomero, Teresa;
- Sulis, Maria Luisa;
- Tosello, Valeria;
- Van Vlierberghe, Pieter;
- Barnes, Kelly;
- Castillo, Mireia;
- Sole, Xavier;
- Hadler, Michael;
- Lenz, Jack;
- Aplan, Peter D.;
- Kelliher, Michelle;
- Kee, Barbara L.;
- Pandolfi, Pier Paolo;
- Kappes, Dietmar;
- Gounari, Fotini;
- Petrie, Howard;
- Van der Meulen, Joni
Publication type:
Article
Ribosomal RNA analysis in the diagnosis of Diamond-Blackfan Anaemia.
Published in:
British Journal of Haematology, 2016, v. 172, n. 5, p. 782, doi. 10.1111/bjh.13880
By:
- Quarello, Paola;
- Garelli, Emanuela;
- Carando, Adriana;
- Mancini, Cecilia;
- Foglia, Luiselda;
- Botto, Carlotta;
- Farruggia, Piero;
- De Keersmaecker, Kim;
- Aspesi, Anna;
- Ellis, Steve R.;
- Dianzani, Irma;
- Ramenghi, Ugo
Publication type:
Article
Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2013, v. 45, n. 2, p. 186, doi. 10.1038/ng.2508
By:
- De Keersmaecker, Kim;
- Atak, Zeynep Kalender;
- Li, Ning;
- Vicente, Carmen;
- Patchett, Stephanie;
- Girardi, Tiziana;
- Gianfelici, Valentina;
- Geerdens, Ellen;
- Clappier, Emmanuelle;
- Porcu, Michaël;
- Lahortiga, Idoya;
- Lucà, Rossella;
- Yan, Jiekun;
- Hulselmans, Gert;
- Vranckx, Hilde;
- Vandepoel, Roel;
- Sweron, Bram;
- Jacobs, Kris;
- Mentens, Nicole;
- Wlodarska, Iwona
Publication type:
Article
Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2010, v. 42, n. 6, p. 530, doi. 10.1038/ng.587
By:
- Kleppe, Maria;
- Lahortiga, Idoya;
- El Chaar, Tiama;
- De Keersmaecker, Kim;
- Mentens, Nicole;
- Graux, Carlos;
- Van Roosbroeck, Katrien;
- Ferrando, Adolfo A;
- Langerak, Anton W;
- Meijerink, Jules P P;
- Sigaux, François;
- Haferlach, Torsten;
- Wlodarska, Iwona;
- Vandenberghe, Peter;
- Soulier, Jean;
- Cools, Jan
Publication type:
Article
Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia.
Published in:
Nature Genetics, 2007, v. 39, n. 5, p. 593, doi. 10.1038/ng2025
By:
- Lahortiga, Idoya;
- De Keersmaecker, Kim;
- Van Vlierberghe, Pieter;
- Graux, Carlos;
- Cauwelier, Barbara;
- Lambert, Frederic;
- Mentens, Nicole;
- Beverloo, H. Berna;
- Pieters, Rob;
- Speleman, Frank;
- Odero, Maria D.;
- Bauters, Marijke;
- Froyen, Guy;
- Marynen, Peter;
- Vandenberghe, Peter;
- Wlodarska, Iwona;
- Meijerink, Jules P. P.;
- Cools, Jan
Publication type:
Article
Optimizing the diagnostic workflow for acute lymphoblastic leukemia by optical genome mapping.
Published in:
American Journal of Hematology, 2022, v. 97, n. 5, p. 548, doi. 10.1002/ajh.26487
By:
- Rack, Katrina;
- De Bie, Jolien;
- Ameye, Geneviève;
- Gielen, Olga;
- Demeyer, Sofie;
- Cools, Jan;
- De Keersmaecker, Kim;
- Vermeesch, Joris R.;
- Maertens, Johan;
- Segers, Heidi;
- Michaux, Lucienne;
- Dewaele, Barbara
Publication type:
Article
High Accuracy Mutation Detection in Leukemia on a Selected Panel of Cancer Genes.
Published in:
PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0038463
By:
- Atak, Zeynep Kalender;
- Keersmaecker, Kim De;
- Gianfelici, Valentina;
- Geerdens, Ellen;
- Vandepoel, Roel;
- Pauwels, Daphnie;
- Porcu, Michaël;
- Lahortiga, Idoya;
- Brys, Vanessa;
- Dirks, Willy G.;
- Quentmeier, Hilmar;
- Cloos, Jacqueline;
- Cuppens, Harry;
- Uyttebroeck, Anne;
- Vandenberghe, Peter;
- Cools, Jan;
- Aerts, Stein
Publication type:
Article
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-10508-2
By:
- Kampen, Kim R.;
- Fancello, Laura;
- Girardi, Tiziana;
- Rinaldi, Gianmarco;
- Planque, Mélanie;
- Sulima, Sergey O.;
- Loayza-Puch, Fabricio;
- Verbelen, Benno;
- Vereecke, Stijn;
- Verbeeck, Jelle;
- Op de Beeck, Joyce;
- Royaert, Jonathan;
- Vermeersch, Pieter;
- Cassiman, David;
- Cools, Jan;
- Agami, Reuven;
- Fiers, Mark;
- Fendt, Sarah-Maria;
- De Keersmaecker, Kim
Publication type:
Article
The DMT1 isoform lacking the iron-response element regulates normal and malignant hematopoiesis via NOTCH pathway activation.
Published in:
FEBS Letters, 2024, v. 598, n. 12, p. 1506, doi. 10.1002/1873-3468.14870
By:
- Hounjet, Judith;
- Van Aerschot, Linde;
- De Keersmaecker, Kim;
- Vooijs, Marc;
- Kampen, Kim R.
Publication type:
Article
Drivers of de novo Serine/Glycine synthesis in acute leukemia.
Published in:
FEBS Letters, 2023, v. 597, n. 17, p. 2145, doi. 10.1002/1873-3468.14700
By:
- Verstraete, Paulien;
- De Keersmaecker, Kim;
- Kampen, Kim Rosalie
Publication type:
Article
Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia.
Published in:
Nature Cell Biology, 2010, v. 12, n. 4, p. 372, doi. 10.1038/ncb2037
By:
- Mavrakis, Konstantinos J.;
- Wolfe, Andrew L.;
- Oricchio, Elisa;
- Palomero, Teresa;
- de Keersmaecker, Kim;
- McJunkin, Katherine;
- Zuber, Johannes;
- James, Taneisha;
- Khan, Aly A.;
- Leslie, Christina S.;
- Parker, Joel S.;
- Paddison, Patrick J.;
- Tam, Wayne;
- Ferrando, Adolfo;
- Wendel, Hans-Guido
Publication type:
Article
Erratum: Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.
Published in:
2010
By:
- Hodson, Daniel J.;
- Janas, Michelle L.;
- Galloway, Alison;
- Bell, Sarah E.;
- Andrews, Simon;
- Li, Cheuk M.;
- Pannell, Richard;
- Siebel, Christian W.;
- MacDonald, H. Robson;
- De Keersmaecker, Kim;
- Ferrando, Adolfo A.;
- Grutz, Gerald;
- Turner, Martin
Publication type:
Correction Notice
Deletion of the RNA-binding proteins ZFP36L1 and ZFP36L2 leads to perturbed thymic development and T lymphoblastic leukemia.
Published in:
Nature Immunology, 2010, v. 11, n. 8, p. 717, doi. 10.1038/ni.1901
By:
- Hodson, Daniel J.;
- Janas, Michelle L.;
- Galloway, Alison;
- Bell, Sarah E.;
- Andrews, Simon;
- Li, Cheuk M.;
- Pannell, Richard;
- Siebel, Christian W.;
- MacDonald, H. Robson;
- De Keersmaecker, Kim;
- Ferrando, Adolfo A.;
- Grutz, Gerald;
- Turner, Martin
Publication type:
Article
Correction: Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer.
Published in:
2024
By:
- Sánchez-Castillo, Anaís;
- Heylen, Elien;
- Hounjet, Judith;
- Savelkouls, Kim G.;
- Lieuwes, Natasja G.;
- Biemans, Rianne;
- Dubois, Ludwig J.;
- Reynders, Kobe;
- Rouschop, Kasper M.;
- Vaes, Rianne D. W.;
- De Keersmaecker, Kim;
- Lambrecht, Maarten;
- Hendriks, Lizza E. L.;
- De Ruysscher, Dirk K. M.;
- Vooijs, Marc;
- Kampen, Kim R.
Publication type:
Correction Notice
Targeting serine/glycine metabolism improves radiotherapy response in non-small cell lung cancer.
Published in:
British Journal of Cancer, 2024, v. 130, n. 4, p. 568, doi. 10.1038/s41416-023-02553-y
By:
- Sánchez-Castillo, Anaís;
- Heylen, Elien;
- Hounjet, Judith;
- Savelkouls, Kim G.;
- Lieuwes, Natasja G.;
- Biemans, Rianne;
- Dubois, Ludwig J.;
- Reynders, Kobe;
- Rouschop, Kasper M.;
- Vaes, Rianne D. W.;
- De Keersmaecker, Kim;
- Lambrecht, Maarten;
- Hendriks, Lizza E. L.;
- De Ruysscher, Dirk K. M.;
- Vooijs, Marc;
- Kampen, Kim R.
Publication type:
Article
Transcription factor NKX2–1 drives serine and glycine synthesis addiction in cancer.
Published in:
British Journal of Cancer, 2023, v. 128, n. 10, p. 1862, doi. 10.1038/s41416-023-02216-y
By:
- Heylen, Elien;
- Verstraete, Paulien;
- Van Aerschot, Linde;
- Geeraerts, Shauni L.;
- Venken, Tom;
- Timcheva, Kalina;
- Nittner, David;
- Verbeeck, Jelle;
- Royaert, Jonathan;
- Gijbels, Marion;
- Uyttebroeck, Anne;
- Segers, Heidi;
- Lambrechts, Diether;
- Cools, Jan;
- De Keersmaecker, Kim;
- Kampen, Kim R.
Publication type:
Article
Cancer Biogenesis in Ribosomopathies.
Published in:
Cells (2073-4409), 2019, v. 8, n. 3, p. 229, doi. 10.3390/cells8030229
By:
- Sulima, Sergey O.;
- Kampen, Kim R.;
- De Keersmaecker, Kim
Publication type:
Article
Hallmarks of ribosomopathies.
Published in:
Nucleic Acids Research, 2020, v. 48, n. 3, p. 1013, doi. 10.1093/nar/gkz637
By:
- Kampen, Kim R;
- Sulima, Sergey O;
- Vereecke, Stijn;
- De Keersmaecker, Kim
Publication type:
Article
Comprehensive Analysis of Transcriptome Variation Uncovers Known and Novel Driver Events in T-Cell Acute Lymphoblastic Leukemia.
Published in:
PLoS Genetics, 2013, v. 9, n. 12, p. 1, doi. 10.1371/journal.pgen.1003997
By:
- Kalender Atak, Zeynep;
- Gianfelici, Valentina;
- Hulselmans, Gert;
- De Keersmaecker, Kim;
- Devasia, Arun George;
- Geerdens, Ellen;
- Mentens, Nicole;
- Chiaretti, Sabina;
- Durinck, Kaat;
- Uyttebroeck, Anne;
- Vandenberghe, Peter;
- Wlodarska, Iwona;
- Cloos, Jacqueline;
- Foà, Robin;
- Speleman, Frank;
- Cools, Jan;
- Aerts, Stein
Publication type:
Article
Exploitation of the ribosomal protein L10 R98S mutation to enhance recombinant protein production in mammalian cells.
Published in:
Engineering in Life Sciences, 2022, v. 22, n. 2, p. 100, doi. 10.1002/elsc.202100124
By:
- Verbelen, Benno;
- Girardi, Tiziana;
- Sulima, Sergey O.;
- Vereecke, Stijn;
- Verstraete, Paulien;
- Verbeeck, Jelle;
- Royaert, Jonathan;
- Cinque, Sonia;
- Montanaro, Lorenzo;
- Penzo, Marianna;
- Imbrechts, Maya;
- Geukens, Nick;
- Geuens, Thomas;
- Dierckx, Koen;
- Pepe, Daniele;
- Kampen, Kim;
- De Keersmaecker, Kim
Publication type:
Article
PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.
Published in:
Journal of Hematology & Oncology, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13045-021-01114-1
By:
- Govaerts, Inge;
- Prieto, Cristina;
- Vandersmissen, Charlien;
- Gielen, Olga;
- Jacobs, Kris;
- Provost, Sarah;
- Nittner, David;
- Maertens, Johan;
- Boeckx, Nancy;
- De Keersmaecker, Kim;
- Segers, Heidi;
- Cools, Jan
Publication type:
Article

Found: 23