We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Characterization of Vaginal Lactobacilli with Potential Probiotic Properties Isolated from Healthy Women in Northern Iran.
- Authors
Zare, Hakimeh; Izadi Amoli, Rabeeh; Rezapour, Maysam; Zaboli, Fatemeh; Kaboosi, Hami
- Abstract
Vaginal lactobacilli protect against bacterial vaginosis and vaginal candidiasis. They may have probiotic properties and help maintain the balance and health of the vaginal ecosystem while the loss of these bacteria predisposes females to urinary and genital infections. The aim of this study was to investigate the probiotic potential of vaginal Lactobacillus among healthy females in northern Iran. The Lactobacillus strains were isolated from vaginal samples and were identified by sequencing of the 16S rRNA fragment. Functional properties such as tolerance to low pH, H2O2 production, adherence ability to Hela cells and antagonistic activity against Candida albicans was examined. A total of 38 vaginal lactobacilli strains from five species, including Lactobacillus crispatus (n = 13), Lactobacillus gasseri (n = 10), Lactobacillus acidophilus (n = 6), Lactobacillus jensenii (n = 5) and Lactobacillus johnsonii (n = 4), were identified. All of the species showed significant tolerance to low pH over 24 h (p < 0.001). The best adherence ability to Hela cells was seen in Lactobacillus gasseri strains. Nearly 17 of the strains had higher anti-candida activity compared to the other strains. According to the findings, four lactobacilli strains isolated in the vaginal samples of healthy Iranian women had the best probiotic potential.
- Subjects
IRAN; PROBIOTICS; LACTOBACILLUS; LACTOBACILLUS acidophilus; VULVOVAGINAL candidiasis; BACTERIAL vaginitis; HELA cells; IRANIANS
- Publication
Indian Journal of Microbiology, 2024, Vol 64, Issue 2, p529
- ISSN
0046-8991
- Publication type
Article
- DOI
10.1007/s12088-023-01186-2