We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Hemangioendotelioma epitelioide primario de metatarsiano. Reporte de un caso.
- Authors
Octavio Castillo-Canto, Carlos; Iván Baltazar-Ramos, Javier; Cadena-Reyes, Jacinto
- Abstract
BACKGROUND: Epithelioid hemangioendothelioma is a rare vascular tumor, symptoms by endothelial and dendritic cells with an epithelioid appearance. At the bone level, it represents <1% of primary tumors, it appears mainly in long bones of the lower extremities, followed by vertebral bodies, bones of the hands and feet. CLINICAL CASE: 56-year-old male patient, with forced inversion of the right foot of five months of evolution and progressive increase in volume in the fifth joint of the same foot. Due to the radiological results, it was decided to obtain a biopsy of the fifth metatarsal, but in the surgical act it was decided to carry out a complete resection of the lesion. Among the histopathological findings, the following stand out: a lesion consisting of a neoplasm with a growth pattern in nests, of variable size and trabeculae, cells with an epithelioid appearance, mild pleomorphism and eosinophilic cytoplasm, formation of cytoplasmic lights and prominent nucleolus; neoformation vessels and thrombi. Extensive ischemic necrosis was identified. Immunohistochemistry reported positive CD31 and Factor VIII. The diagnosis of epithelioid hemangioendothelioma was established. CONCLUSION: Although there are no established treatment guidelines for this neoplasm, traditionally surgical resection with wide margins has been chosen, reserving radiotherapy and chemotherapy for patients with multiple tumors or those with difficult access for the surgical procedure.
- Subjects
TUMOR growth; OPERATIVE surgery; DIAGNOSIS; SURGICAL margin; MULTIPLE tumors; FOOT; FROZEN tissue sections
- Publication
Patologia Revista Latinoamericana, 2020, Vol 58, p1
- ISSN
0185-4305
- Publication type
Article
- DOI
10.24245/patrl.v58id.4316