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- Title
Immunopathology of Dirofilaria immitis Infection.
- Authors
F. Simón; L. Kramer; R. Morchón; C. Marcos-Atxutegi; G. Grandi; C. Genchi
- Abstract
Abstract??Heartworm disease caused byDirofilaria immitisaffects canine and feline hosts, with infections occasionally being reported in humans. Studies have shown that both dirofilarial antigens and those derived from its bacterial endosymbiontWolbachia,interact with the host organism during canine, feline and human infections and participate in the development of the pathology and in the regulation of the host?s immune response. Both innate and acquired immune responses are observed and the development of the acquired response may depend on the host and, or on its parasitological status. This review aims at illustrating current research on the role of bothD. immitisandWolbachia, in the immunology and immunopathology of dirofilariosis.
- Subjects
DIROFILARIA; CLINICAL immunology; DIPETALONEMATIDAE; DOG parasites
- Publication
Veterinary Research Communications, 2007, Vol 31, Issue 2, p161
- ISSN
0165-7380
- Publication type
Article