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- Title
Primary Sclerosing Cholangitis: Evolving Concepts in Diagnosis and Treatment.
- Authors
Harnois, Denise M.; Lindor, Keith D.
- Abstract
Primary sclerosing cholangitis is an increasingly recognized cause of chronic cholestatic liver disease. The etiology is unknown, although a number of immunologic and nonimmunologic factors have been considered. The most important diagnostic findings are diffuse irregularity and narrowing of extrahepatic and intrahepatic bile ducts. The prognosis varies, and a number of relatively unique complications may develop. No adequate treatment exists, although a number of potential treatments have been evaluated. Liver transplantation still remains the most appropriate treatment for end-stage disease. These various topics related to primary sclerosing cholangitis are reviewed. Copyright © 1997 S. Karger AG, Basel
- Publication
Digestive Diseases, 1997, Vol 15, Issue 1/2, p23
- ISSN
0257-2753
- Publication type
Article
- DOI
10.1159/000171586