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- Title
Metal-catalyzed privileged 2- and 3-functionalized indole synthesis*.
- Authors
Sinha, Arun K.; Equbal, Danish; Uttam, Mane Rajendra
- Abstract
<graphic></graphic>This review summarizes the metal-catalyzed approaches for the synthesis of privileged 2- and 3-functionalized indoles via the Fischer indole synthesis, cycloaddition reaction, C-H activation reaction, and coupling reactions. Polycyclic derivatives of indole are also listed including triptamine-based pharmaceutical 5-HT1D agonist L 775,606. Some important mechanism studies are described in details in this review. The review covers literature for the last 20 years.
- Subjects
INDOLE; HETEROCYCLIC compounds; CARBON-hydrogen bonds; METAL catalysts; ORGANIC cyclic compounds
- Publication
Chemistry of Heterocyclic Compounds, 2018, Vol 54, Issue 3, p292
- ISSN
0009-3122
- Publication type
Article
- DOI
10.1007/s10593-018-2263-5