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- Title
Apport de la thymectomie dans le traitement de la myasthénie généralisée.
- Authors
Issoufou, Ibrahim; Sani, Rabiou; Harmouchi, Hicham; Amadou, Daouda; Lakranbi, Marouane; Sani, Rachid; El Bouazzaoui, Abderrahim; Ouadnouni, Yassine; Smahi, Mohamed
- Abstract
The aim of our study is to show the contribution of thymectomies in the treatment of myasthenia gravis. Patients and méthode: this was a descriptive and retrospective study carried out in the thoracic surgery department of the teaching hospital Hassan II in Fez during the period May 2009-May 2018. It concerned all the patients who had undergone a thymectomy by median sternotomy for myasthenia gravis. The results of this surgery were evaluated by a neurologist using the scale of the Myasthenia Gravis Foundation of America (MGFA). Results: this was a series of 34 myasthenic patients who underwent a thymectomy. There were 24 women and 10 men with an average age of 34. Clinical signs were classified according to Osserman’s myasthenic score. Thus, after surgery, a significant decrease in symptoms and drug doses was observed in 68% of cases, while it was unchanged in 18%. In addition, univariate analysis showed a statistically significant correlation (p = 0.02) between female sex and improved patients after surgery. Likewise, the improved patients had B1 and B2 thymoma in 56 and 44% respectively, while those in the “unchanged” group had B1 and B3 thymoma in 50% each. Conclusion: thymectomy provides clinical improvement and better quality of life for myasthenic patients with very low morbidity and mortality. It must be carried out in centers experienced in this task with intensive care units used to this kind of care.
- Subjects
THYMECTOMY; MYASTHENIA gravis; NEUROMUSCULAR diseases; UNIVARIATE analysis; QUALITY of life; DISEASES
- Publication
Cahiers Santé - Médecine Thérapeutique, 2023, Vol 32, Issue 5, p249
- ISSN
2780-8858
- Publication type
Article
- DOI
10.1684/sanmt.2023.210