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- Title
Anti-SARS-CoV-2 Vaccination and PIMS-TS—Friends or Foe? Case Reports and Literature Review.
- Authors
Opoka-Winiarska, Violetta; Morawska-Michalska, Izabela; Mertowska, Paulina; Gosik, Krzysztof; Kądziołka, Olga; Grywalska, Ewelina
- Abstract
Pediatric inflammatory, multisystem syndrome temporally associated with SARS-CoV-2 infection (PIMS-TS), also known as a multisystem inflammatory syndrome in children (MIS-C), is diagnosed in children who develop an inadequate inflammatory response after exposure to the SARS-CoV-2 virus. The pathogenesis of the abnormal response of the immune system to a previous SARS-COV-2 infection has not been explained. Similarly, the safety and effectiveness of COVID-19 vaccinations in this group of patients have become the subject of clinical discussion. Presenting experiences from many centers aims to answer this question. We present 4 cases of patients who suffered from PIMS-TS. Three of them were safely vaccinated against COVID-19 after illness. One patient developed PIMS-TS temporarily associated with COVID-19 vaccination. We also collected and discussed data from other centers.
- Subjects
MULTISYSTEM inflammatory syndrome in children; LITERATURE reviews; COVID-19 vaccines; SARS-CoV-2; VACCINATION
- Publication
Vaccines, 2024, Vol 12, Issue 3, p278
- ISSN
2076-393X
- Publication type
Article
- DOI
10.3390/vaccines12030278