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- Title
Identifying and managing inhibitor patients requiring orthopaedic surgery – the multidisciplinary team approach.
- Authors
Ludlam, C.
- Abstract
Until recently, surgery in haemophilia patients with inhibitors was strongly contraindicated and was therefore often not even contemplated. Inhibitor patients entering the surgical arena face unique challenges; the most frequently encountered problem during surgical intervention is bleeding, and thrombosis is occasionally observed. The activated prothrombin complex concentrate, FEIBA TM, and recombinant activated factor VII (rFVIIa) are available as haemostatic cover during surgery. The use of rFVIIa enables inhibitor patients to undergo orthopaedic surgery with an expectation of success, and results are generally good. An organized team approach is critical to this success. However, further information is required to enable different procedures to be optimized in terms of both outcome and safety.
- Subjects
HEMOPHILIACS; ORTHOPEDIC surgery; MEDICAL practice; MULTIDISCIPLINARY practices; SURGICAL complications; HEMORRHAGE; HEMOSTATICS
- Publication
Haemophilia, 2005, Vol 11, p7
- ISSN
1351-8216
- Publication type
Article
- DOI
10.1111/j.1365-2516.2005.01152.x