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- Title
Cell Based Autologous Immune Enhancement Therapy (AIET) after Radiotherapy in a Locally Advanced Carcinoma of the Cervix.
- Authors
Premkumar, Sumana; Dedeepiya, Vidyasagar Devaprasad; Hiroshi Terunuma; Senthilkumar, Rajappa; Srinivasan, Thangavelu; Reena, Helen C.; Preethy, Senthilkumar; Abraham, Samuel J. K.
- Abstract
Radiotherapy is the primary form of treatment in patients with locally advanced cervical carcinoma. However for residual disease in the form of the persistent lymph nodes, surgery or chemotherapy is recommended. As surgery is not acceptable by every patient and chemotherapy has associated side effects, we hereby report the positive outcome of in vitro expanded natural killer cell and activated T lymphocyte based autologous immune enhancement therapy (AIET) for the residual lymphadenopathy in a patient with locally advanced cervical cancer after radiation. After six transfusions of AIET, there was complete resolution of residual lymph nodes and there was no evidence of local lesion. The patient also reported improvement in quality of life. As AIET has been reported as the least toxic among the available therapies for cancer, combining AIET with conventional forms of therapy in similar patients might not only improve the outcome but may also help the patients achieve a good quality of life.
- Subjects
CERVICAL cancer treatment; CANCER radiotherapy; CANCER chemotherapy; CANCER immunotherapy; KILLER cells; T cells; HEALTH outcome assessment
- Publication
Case Reports in Oncological Medicine, 2013, p1
- ISSN
2090-6706
- Publication type
Article
- DOI
10.1155/2013/903094