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- Title
Determination of Lipid Derangements in Human Immunodeficiency Virus Patients Undergoing Anti-Retroviral Therapy.
- Authors
Bashir, Qamar; Haroon, Zujaja Hina; Asif, Naveed; Khan, Muhammad Qaiser Alam; Ghani, Eijaz; Jaffar, Syed Raza
- Abstract
Objective: To determine lipid derangements in HIV-positive patients receiving anti-retroviral therapy (ART). Study Design: Comparative cross-sectional study. Place and Duration of study: Chemical Pathology Department, in cooperation with the Department of Virology at Armed Forces Institute of Pathology (AFIP), Rawalpindi Pakistan, from Mar 2019 to Mar 2020. Methodology: In this study, two groups were made. In Group-1, lipid profile estimation was done in HIV patients without treatment. In contrast, lipid profile estimation was done after one year of treatment with anti-retroviral drugs in Group-2. Results: One hundred and two HIV-positive subjects were included in our study. Of these patients, 88(86.27%) were males, and 14(13.73%) were females. Independent sample t-test revealed a statistically significant difference (p-value<0.05) in serum cholesterol, serum triglycerides, serum high-density lipoprotein (HDL-c), low-density lipoproteins (LDL) and very low-density lipoproteins (VLDL) between the two groups. Conclusion: Hyperlipidemia in HIV patients getting anti-retroviral therapy (ART) exposes them to a high risk of coronary artery diseases and myocardial infarction. Hence lipid profile of patients getting ART must be regularly monitored, and hyperlipidemia, if present, should be managed.
- Subjects
RAWALPINDI (Pakistan); PAKISTAN; HIV; ANTIRETROVIRAL agents; LOW density lipoproteins; AIDS; LIPIDS
- Publication
Pakistan Armed Forces Medical Journal, 2022, Vol 72, Issue 6, p1871
- ISSN
0030-9648
- Publication type
Abstract
- DOI
10.51253/pafmj.v72i6.5810