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- Title
EFFECTS OF UNILATERAL INTRAVITREAL BEVACIZUMAB ON THE CONTRALATERAL EYE HAVING DIABETIC MACULAR EDEMA.
- Authors
Bashir, Aziz Jan; Hannan, Abdul; Chaudhary, Salman Sohail; Zafar, Sarah; Syed, Abdullah Naeem; Massana, Syed Hassan
- Abstract
Objective: To investigate the effect of unilateral intravitreal Bevacizumab on contralateral eye in bilateral diabetic macular edema. Study Design: Quasi-experimental study. Place and Duration of Study: Retina Department of Al-Shifa Trust Eye Hospital, Rawalpindi, from Sep to Dec 2020. Methodology: Thirty-two patients were enrolled with consecutive sampling. All the patients had clinically diagnosed diabetic macular edema having >275μm macular thickness on OCT. They were injected with 1.25mg/0.05mL of Bevacizumab in one eye. Baseline macular thickness was compared with 4 weeks follow up macular thickness, using Optical Coherence Tomography. Results: The central macular thickness in the untreated eye at baseline was 396.97 ± 29.79 μm and 388.34 ± 30.06 μm at 4 weeks (p-value=0.001). The difference in central macular thickness in treated and untreated eyes were 28.44 ± 4.11 μm and 19.81 ± 5.31 μm respectively (p-value = 0.001). There were statistically significant differences between these measurements. Conclusion: Injecting Bevacizumab in one eye for diabetic macular edema has statistically significant effect on the contralateral non-injected eye macular thickness.
- Subjects
RAWALPINDI (Pakistan); MACULAR edema; BEVACIZUMAB; OPTICAL coherence tomography; RETINA
- Publication
Pakistan Armed Forces Medical Journal, 2021, Vol 71, Issue 6, p2075
- ISSN
0030-9648
- Publication type
Abstract
- DOI
10.51253/pafmj.v6i6.5853