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- Title
Proteus syndrome: A rare cause of gigantic limb.
- Authors
Chakrabarti, Nandini; Chattopadhyay, Chandan; Bhuban, Majhi; Pal, Salil Kumar
- Abstract
A congenital disorder with variable manifestations, including partial gigantism of the hands and feet with hypertrophy of soles, nevi, hemihypertrophy, gynecomastia, macrocephaly and other skull abnormalities, and abdominal lipomatosis. The cause is unknown, although a genetic origin, generally of autosomal-dominant transmission, has been conjectured. Symptoms can be treated, but there is no known cure. We present the case of a young male with grotesque overgrowth of the right lower limb, splenomegaly and multiple nevi. Angiography revealed venous malformation within the limb. The findings are in conformity to the criteria for the Proteus syndrome.
- Subjects
PROTEUS syndrome; CONGENITAL disorders; GIGANTISM (Disease); HYPERTROPHY; GYNECOMASTIA
- Publication
Indian Dermatology Online Journal, 2014, Vol 5, Issue 2, p193
- ISSN
2229-5178
- Publication type
Case Study
- DOI
10.4103/2229-5178.131108