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- Title
Autologous stem-cell transplantation for multiple myeloma: a Brazilian institution experience in 15 years of follow-up.
- Authors
Todaro, Juliana; Burgos Manhani, Ana Rita de Araújo; Kutner, José Mauro; Ribeiro, Andreza Alice Feitosa; Rodrigues, Morgani; Kerbauy, Fabio Rodrigues; Sobrinho, Jairo Nascimento; Ferreira, Eurípedes; Hamerschlak, Nelson
- Abstract
Objective: To determine the 5-year post-transplant survival of patients with multiple myeloma. Methods: A retrospective study in patients diagnosed with multiple myeloma submitted to autologous bone marrow transplantation at a Brazilian institution, during the period of 1993 to 2007. Results: Seventy-three patients were evaluated with a median age of 55 years. Survival in 5 years was 75% (2.4 to 60 months). Statistical analysis demonstrated statistical significance for the applied grade of response prior to treatment with autologous bone marrow transplantation (p = 0.01). There was no statistical significance for clinical staging or time of diagnosis (before or after the year 2000). Conclusion: Experience in autologous bone marrow transplantation for multiple myeloma at a Brazilian institution demonstrated an evolution consistent with that of medical literature and highlighted the importance of a response to treatment prior to transplantation in the survival of these patients.
- Subjects
BRAZIL; MULTIPLE myeloma; STEM cell transplantation; BONE marrow transplantation; IMMUNE system; RETROSPECTIVE studies
- Publication
Einstein (16794508), 2011, Vol 9, Issue 2, p119
- ISSN
1679-4508
- Publication type
Article
- DOI
10.1590/s1679-45082011ao1845