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- Title
Induction of maxillary and mandibular squamous epithelial cell proliferation in mink (Neovison vison) by β‐naphthoflavone.
- Authors
Matz, Danielle K.; Chuck, Joanna; Hosmer, Robin J.; Piper, Hannah C.; Link, Jane E.; Fitzgerald, Scott D.; Steibel, Juan P.; Bursian, Steven J.
- Abstract
A jaw lesion reported in mink exposed to 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) and TCDD‐like chemicals is considered a potential indicator of exposure to these chemicals. Many of the effects of TCDD‐like chemicals are induced through interaction with the aryl hydrocarbon receptor. The present study indicates that mink dosed with β‐naphthoflavone, which is an aryl hydrocarbon receptor ligand but not a TCDD‐like chemical, also develop the lesion. Environ Toxicol Chem 2019;38:460–463. © 2018 SETAC
- Subjects
AMERICAN mink; CELL proliferation; TETRACHLORODIBENZODIOXIN; MAXILLA; TISSUE wounds; MANDIBLE injuries; EPITHELIAL cells; ARYL hydrocarbon receptors; MAMMALS
- Publication
Environmental Toxicology & Chemistry, 2019, Vol 38, Issue 2, p460
- ISSN
0730-7268
- Publication type
Article
- DOI
10.1002/etc.4329