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Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.918083
By:
- Wang, Amy Q.;
- Hagen, Natalie R.;
- Padilha, Elias C.;
- Mengbi Yang;
- Shah, Pranav;
- Chen, Catherine Z.;
- Huang, Wenwei;
- Terse, Pramod;
- Sanderson, Philip;
- Wei Zheng;
- Xin Xu
Publication type:
Article
Therapeutic Strategies For Tay-Sachs Disease.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.906647
By:
- Picache, Jaqueline A.;
- Wei Zheng;
- Chen, Catherine Z.
Publication type:
Article
Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics.
Published in:
2017
By:
- Aguisanda, Francis;
- Yeh, Charles D.;
- Chen, Catherine Z.;
- Rong Li;
- Beers, Jeanette;
- Jizhong Zou;
- Thorne, Natasha;
- Wei Zheng;
- Li, Rong;
- Zou, Jizhong;
- Zheng, Wei
Publication type:
journal article
Genetic Analysis of Yeast Yip1p Function Reveals a Requirement for Golgi-Localized Rab Proteins and Rab-Guanine Nucleotide Dissociation Inhibitor.
Published in:
Genetics, 2004, v. 168, n. 4, p. 1827, doi. 10.1534/genetics.104.032888
By:
- Chen, Catherine Z.;
- Calero, Monica;
- DeRegis, Carol J.;
- Heidtman, Matthew;
- Barlowe, Charles;
- Coffins, Ruth N.
Publication type:
Article
Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 10, p. 6591, doi. 10.1093/nar/gku275
By:
- Hoskins, Jason W.;
- Ofori, Leslie O.;
- Chen, Catherine Z.;
- Kumar, Amit;
- Sobczak, Krzysztof;
- Nakamori, Masayuki;
- Southall, Noel;
- Patnaik, Samarjit;
- Marugan, Juan J.;
- Zheng, Wei;
- Austin, Christopher P.;
- Disney, Matthew D.;
- Miller, Benjamin L.;
- Thornton, Charles A.
Publication type:
Article
Biological activity-based modeling identifies antiviral leads against SARS-CoV-2.
Published in:
Nature Biotechnology, 2021, v. 39, n. 6, p. 747, doi. 10.1038/s41587-021-00839-1
By:
- Huang, Ruili;
- Xu, Miao;
- Zhu, Hu;
- Chen, Catherine Z.;
- Zhu, Wei;
- Lee, Emily M.;
- He, Shihua;
- Zhang, Li;
- Zhao, Jinghua;
- Shamim, Khalida;
- Bougie, Danielle;
- Huang, Wenwei;
- Xia, Menghang;
- Hall, Mathew D.;
- Lo, Donald;
- Simeonov, Anton;
- Austin, Christopher P.;
- Qiu, Xiangguo;
- Tang, Hengli;
- Zheng, Wei
Publication type:
Article
A role for Yip 1p in COPII Vesicle biogenesis.
Published in:
Journal of Cell Biology, 2003, v. 163, n. 1, p. 57, doi. 10.1083/jcb.200306118
By:
- Heidtman, Matthew;
- Chen, Catherine Z.;
- Collins, Ruth N.;
- Barlowe, Charles
Publication type:
Article
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.
Published in:
Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.592737
By:
- Chen, Catherine Z.;
- Shinn, Paul;
- Itkin, Zina;
- Eastman, Richard T.;
- Bostwick, Robert;
- Rasmussen, Lynn;
- Huang, Ruili;
- Shen, Min;
- Hu, Xin;
- Wilson, Kelli M.;
- Brooks, Brianna M.;
- Guo, Hui;
- Zhao, Tongan;
- Klump-Thomas, Carleen;
- Simeonov, Anton;
- Michael, Samuel G.;
- Lo, Donald C.;
- Hall, Matthew D.;
- Zheng, Wei
Publication type:
Article
Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41453-w
By:
- Zhang, Qi;
- Tang, Weichun;
- Stancanelli, Eduardo;
- Jung, Eunkyung;
- Syed, Zulfeqhar;
- Pagadala, Vijayakanth;
- Saidi, Layla;
- Chen, Catherine Z.;
- Gao, Peng;
- Xu, Miao;
- Pavlinov, Ivan;
- Li, Bing;
- Huang, Wenwei;
- Chen, Liqiang;
- Liu, Jian;
- Xie, Hang;
- Zheng, Wei;
- Ye, Yihong
Publication type:
Article
A High Throughput Screening Assay System for the Identification of Small Molecule Inhibitors of <i>gsp</i>.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090766
By:
- Bhattacharyya, Nisan;
- Hu, Xin;
- Chen, Catherine Z.;
- Mathews Griner, Lesley A.;
- Zheng, Wei;
- Inglese, James;
- Austin, Christopher P.;
- Marugan, Juan J.;
- Southall, Noel;
- Neumann, Susanne;
- Northup, John K.;
- Ferrer, Marc;
- Collins, Michael T.
Publication type:
Article
Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1.
Published in:
Nature Communications, 2013, v. 4, n. 6, p. 1953, doi. 10.1038/ncomms2953
By:
- Xiao, Jingbo;
- Huang, Zaohua;
- Chen, Catherine Z.;
- Agoulnik, Irina U.;
- Southall, Noel;
- Hu, Xin;
- Jones, Raisa E.;
- Ferrer, Marc;
- Zheng, Wei;
- Agoulnik, Alexander I.;
- Marugan, Juan J.
Publication type:
Article
Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules.
Published in:
Nature Communications, 2013, v. 4, n. 6, p. 2044, doi. 10.1038/ncomms3044
By:
- Childs-Disney, Jessica L.;
- Stepniak-Konieczna, Ewa;
- Tran, Tuan;
- Yildirim, Ilyas;
- Park, HaJeung;
- Chen, Catherine Z.;
- Hoskins, Jason;
- Southall, Noel;
- Marugan, Juan J.;
- Patnaik, Samarjit;
- Zheng, Wei;
- Austin, Chris P.;
- Schatz, George C.;
- Sobczak, Krzysztof;
- Thornton, Charles A.;
- Disney, Matthew D.
Publication type:
Article
Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86110-8
By:
- Zhu, Hu;
- Chen, Catherine Z.;
- Sakamuru, Srilatha;
- Zhao, Jinghua;
- Ngan, Deborah K.;
- Simeonov, Anton;
- Hall, Mathew D.;
- Xia, Menghang;
- Zheng, Wei;
- Huang, Ruili
Publication type:
Article
Repurposing a novel parathyroid hormone analogue to treat hypoparathyroidism.
Published in:
2018
By:
- Krishnan, Venkatesh;
- Ma, Yanfei L.;
- Chen, Catherine Z.;
- Thorne, Natasha;
- Bullock, Heather;
- Tawa, Gregory;
- Javella‐Cauley, Christy;
- Chu, Shaoyou;
- Li, Weiming;
- Kohn, Wayne;
- Adrian, Mary D.;
- Benson, Charles;
- Liu, Lifei;
- Sato, Masahiko;
- Zheng, Wei;
- Pilon, Andre M.;
- Yang, N. Nora;
- Bryant, Henry U.;
- Javella-Cauley, Christy
Publication type:
journal article
High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell lines.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 6, p. 1551, doi. 10.1093/hmg/ddt542
By:
- Ketley, Ami;
- Chen, Catherine Z.;
- Li, Xin;
- Arya, Sukrat;
- Robinson, Thelma E.;
- Granados-Riveron, Javier;
- Udosen, Inyang;
- Morris, Glenn E.;
- Holt, Ian;
- Furling, Denis;
- Chaouch, Soraya;
- Haworth, Ben;
- Southall, Noel;
- Shinn, Paul;
- Zheng, Wei;
- Austin, Christopher P.;
- Hayes, Christopher J.;
- Brook, J. David
Publication type:
Article
A humanized nanobody phage display library yields potent binders of SARS CoV-2 spike.
Published in:
PLoS ONE, 2022, v. 17, n. 8, p. 1, doi. 10.1371/journal.pone.0272364
By:
- Fu, Ying;
- da Fonseca Rezende e Mello, Juliana;
- Fleming, Bryan D.;
- Renn, Alex;
- Chen, Catherine Z.;
- Hu, Xin;
- Xu, Miao;
- Gorshkov, Kirill;
- Hanson, Quinlin;
- Zheng, Wei;
- Lee, Emily M.;
- Perera, Lalith;
- Petrovich, Robert;
- Pradhan, Manisha;
- Eastman, Richard T.;
- Itkin, Zina;
- Stanley, Thomas B.;
- Hsu, Allen;
- Dandey, Venkata;
- Sharma, Kedar
Publication type:
Article
A Protocol for Culture and Characterization of Human Induced Pluripotent Stem Cells After Induction.
Published in:
Current Protocols, 2023, v. 3, n. 8, p. 1, doi. 10.1002/cpz1.866
By:
- Cheng, Yu‐Shan;
- Xu, Miao;
- Chen, Guibin;
- Beers, Jeanette;
- Chen, Catherine Z.;
- Liu, Chengyu;
- Zou, Jizhong;
- Zheng, Wei
Publication type:
Article

Found: 17