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- Title
Coinfection and Superinfection in Patients with Long-Term, Nonprogressive HIV-1 Disease.
- Authors
Casado, Concepción; Pernas, Maria; Alvaro, Tamara; Sandonis, Virginia; García, Soledad; Rodríguez, Carmen; del Romero, Jorge; Grau, Eulalia; Ruiz, Lidia; Lopez-Galindez, Cecilio
- Abstract
Human immunodeficiency virus 1 (HIV-1) dual infections are considered important because they have been related to AIDS progression. We identified dual infections in 2 patients with long-term, nonprogressive HIV-1 disease; the first patient was diagnosed as being already coinfected, on the basis of the first sample analyzed, but a previous superinfection could not be excluded; the second patient was diagnosed as having a superinfection, on the basis of the 9-year difference between the viral dating of the 2 strains. Dual infections occur in patients with long-term, nonprogressive disease, with no immediate clinical manifestations. Such occurrences could indicate a general phenomenon in natural HIV-1 infections.
- Subjects
HIV infections; HIV; HIV-positive persons; INFECTION; AIDS; COMMUNICABLE diseases; MEDICAL microbiology; VIRUS research; MEDICAL research
- Publication
Journal of Infectious Diseases, 2007, Vol 196, Issue 6, p895
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/520885