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- Title
Incidence of Resistance in a Double-Blind Study Comparing Lopinavir/Ritonavir Plus Stavudine and Lamivudine to Nelfinavir plus Stavudine and Lamivudine.
- Authors
Kempf, Dale J.; King, Martin S.; Bernstein, Barry; Cernohous, Paul; Bauer, Eric; Moseley, Jennifer; Kai Gu, Jennifer; Hsu, Ann; Brun, Scott; Sun, Eugene
- Abstract
Reports on the incidence of resistance in a double-blind study comparing lopinavir/ritonavir plus stavudine and lamivudine to nelfinavir plus stavudine and lamivudine in anteroretroviral therapy-naive human immunodeficiency virus (HIV) type 1-infected subjects. Study methods; Primary mutations related to nelfinavir resistance; Different genetic and pharmacological barriers to resistance.
- Subjects
ANTIRETROVIRAL agents; DRUG resistance; HIV infections; THERAPEUTICS; HIV-positive persons; DRUG efficacy; ANTIVIRAL agents
- Publication
Journal of Infectious Diseases, 2004, Vol 189, Issue 1, p51
- ISSN
0022-1899
- Publication type
Article
- DOI
10.1086/380509