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- Title
Acute Responses of Inflammatory Markers of Cardiovascular Disease Risk to a Single Walking Session.
- Authors
Murtagh, Elaine M.; Boreham, Colin; Nevill, Alan; Davison, Gareth; Trinick, Tom; Duly, Ellie; El-Agnaf, Mawloud; Murphy, Marie H.
- Abstract
Markers of inflammation are emerging as novel indices of cardio-vascular risk. These markers have been shown to alter acutely after intense exercise; however, the effects of more moderate intensity exercise in healthy individuals is not known. Walking forms a cornerstone of physical activity promotion, so the inflammatory response to this exercise merits investigation. This study evaluated the effects of a 45-min walk on C-reactive protein (CRP) and interleukin 6 (IL-6), in sedentary, overweight men. Methods: Fifteen men (49.7 ± 5.9 y) walked for 45 min at 60 to 70% of predicted maximum heart rate. Fasted blood samples were taken prior to and immediately 1 hr and 24 h post-walk. Results: IL-6 decreased from 1 h post-walk to 24 h post-walk (P < 0.01). No significant changes were observed in CRP. Conclusions: These findings suggest that 45 min walking at 60 to 70% HRmax-p causes a decrease in IL-6 24 h post-exercise, but does not evoke a significant response in CRP levels.
- Subjects
DISEASE risk factors; CARDIOVASCULAR diseases; INFLAMMATORY mediators; WALKING; PHYSICAL fitness; EXERCISE; HEALTH
- Publication
Journal of Physical Activity & Health, 2005, Vol 2, Issue 3, p324
- ISSN
1543-3080
- Publication type
Article
- DOI
10.1123/jpah.2.3.324