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- Title
Zinc Improves Semen Parameters in High-Fat Diet-Induced Male Rats by Regulating the Expression of LncRNA in Testis Tissue.
- Authors
Ma, Jing; Bi, Jiajie; Sun, Bo; Li, Huanhuan; Li, Yuejia; Wang, Shusong
- Abstract
This study aimed to identify differentially expressed LncRNAs in testis tissue of male rats induced by high-fat diet and their changes after zinc supplementation, by constructing a high-fat feeding rat model, and then supplemented with zinc, and observed the expression of LncRNA in three groups of normal, high-fat fed, and zinc-intervened rats. Experimental studies show that the semen parameters of male rats with high-fat diet were decreased but recovered after zinc supplementation, and the related LncRNA also changed. Zinc may improve the high-fat diet-induced reduction of semen parameters by changing the expression of related LncRNA.
- Subjects
SEMEN; LINCRNA; TESTIS; ZINC; ZINC supplements; SPERMATOGENESIS; GONADS; FAT
- Publication
Biological Trace Element Research, 2023, Vol 201, Issue 10, p4793
- ISSN
0163-4984
- Publication type
Article
- DOI
10.1007/s12011-022-03550-7