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In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-03590-4
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- Article
Operational Determination of Subjective Cognitive Decline, Mild Cognitive Impairment, and Dementia Using Sum of Boxes of the Clinical Dementia Rating Scale.
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- Frontiers in Aging Neuroscience, 2021, v. 13, p. 1, doi. 10.3389/fnagi.2021.705782
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- Article
The role of ubiquitin-specific peptidases in cancer progression.
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- Journal of Biomedical Science, 2019, v. 26, n. 1, p. N.PAG, doi. 10.1186/s12929-019-0522-0
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- Article
Crowning Proteins: Modulating the Protein Surface Properties using Crown Ethers.
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- Angewandte Chemie International Edition, 2014, v. 53, n. 48, p. 13054, doi. 10.1002/anie.201405664
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- Article
Dibenzofuran, 4-Chromanone, Acetophenone, and Dithiecine Derivatives: Cytotoxic Constituents from Eupatorium fortunei.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7448, doi. 10.3390/ijms22147448
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- Article
Nicotinic Acetylcholine Receptor Subunit Alpha-5 Promotes Radioresistance via Recruiting E2F Activity in Oral Squamous Cell Carcinoma.
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- Journal of Clinical Medicine, 2019, v. 8, n. 9, p. 1454, doi. 10.3390/jcm8091454
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- Publication type:
- Article
In vitro characterization of a small molecule PD-1 inhibitor that targets the PD-l/PD-L1 interaction.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-03590-4
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- Publication type:
- Article
Using structural-based protein engineering to modulate the differential inhibition effects of SAUGI on human and HSV uracil DNA glycosylase.
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- Nucleic Acids Research, 2016, v. 44, n. 9, p. 4440, doi. 10.1093/nar/gkw185
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- Article
Staphylococcus aureus protein SAUGI acts as a uracil-DNA glycosylase inhibitor.
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- Nucleic Acids Research, 2014, v. 42, n. 2, p. 1354, doi. 10.1093/nar/gkt964
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- Article
KIDFamMap: a database of kinase-inhibitor-disease family maps for kinase inhibitor selectivity and binding mechanisms.
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- Nucleic Acids Research, 2013, v. 41, p. D430, doi. 10.1093/nar/gks1218
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- Article
SiMMap: a web server for inferring site-moiety map to recognize interaction preferences between protein pockets and compound moieties.
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- Nucleic Acids Research, 2010, v. 38, n. suppl_2, p. W424, doi. 10.1093/nar/gkq480
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- Article
ATRIPPI:: AN ATOM-RESIDUE PREFERENCE SCORING FUNCTION FOR PROTEIN–PROTEIN INTERACTIONS.
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- International Journal on Artificial Intelligence Tools, 2010, v. 19, n. 3, p. 251, doi. 10.1142/S0218213010000169
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- Article
Patient and hospital characteristics associated with do-not-resuscitate/do-not-intubate orders: a cross-sectional study based on the Taiwan stroke registry.
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- BMC Palliative Care, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12904-023-01257-7
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- Article
Crowning Proteins: Modulating the Protein Surface Properties using Crown Ethers.
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- Angewandte Chemie, 2014, v. 126, n. 48, p. 13270, doi. 10.1002/ange.201405664
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- Publication type:
- Article
Utility of polygenic scores across diverse diseases in a hospital cohort for predictive modeling.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-47472-5
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- Article
Impacts of Autophagy-Inducing Ingredient of Areca Nut on Tumor Cells.
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- PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0128011
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- Article
Parallel Screening of Wild-Type and Drug-Resistant Targets for Anti-Resistance Neuraminidase Inhibitors.
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- PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056704
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- Article
Structures of Helicobacter pylori Shikimate Kinase Reveal a Selective Inhibitor-Induced-Fit Mechanism.
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- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033481
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- Article
Core Site-Moiety Maps Reveal Inhibitors and Binding Mechanisms of Orthologous Proteins by Screening Compound Libraries.
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- PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0032142
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- Article
Sum of boxes of the clinical dementia rating scale highly predicts conversion or reversion in predementia stages.
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- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.1021792
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- Article
LDOC1 Suppresses Microbe-Induced Production of IL-1β in Human Normal and Cancerous Oral Cells through the PI3K/Akt/GSK-3β Axis.
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- Cancers, 2020, v. 12, n. 11, p. 3148, doi. 10.3390/cancers12113148
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- Article
Novel Three-Port Bidirectional DC/DC Converter with Three-Winding Coupled Inductor for Photovoltaic System.
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- Energies (19961073), 2020, v. 13, n. 5, p. 1132, doi. 10.3390/en13051132
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- Article
Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5‐diamino‐6‐chloro‐N‐(N‐(2,6‐dichlorobenzoyl)carbamimidoyl)pyrazine‐2‐carboxide.
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- Molecular Oncology, 2019, v. 13, n. 8, p. 1744, doi. 10.1002/1878-0261.12524
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- Article
From Sea to Science: Coral Aquaculture for Sustainable Anticancer Drug Development.
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- Marine Drugs, 2024, v. 22, n. 7, p. 323, doi. 10.3390/md22070323
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- Article
13-Acetoxysarcocrassolide Exhibits Cytotoxic Activity against Oral Cancer Cells through the Interruption of the Keap1/Nrf2/p62/SQSTM1 Pathway: The Need to Move Beyond Classical Concepts.
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- Marine Drugs, 2020, v. 18, n. 8, p. 382, doi. 10.3390/md18080382
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- Article
Structural Insights into the Cytotoxic Mechanism of Vibrio parahaemolyticus PirA<sup>vp</sup> and PirB<sup>vp</sup> Toxins.
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- Marine Drugs, 2017, v. 15, n. 12, p. 373, doi. 10.3390/md15120373
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- Article
Comparing the Long-Term Cardiovascular Outcomes of Lumbo-Peritoneal, Ventriculo-Peritoneal, or Non-Shunting Treatment after Idiopathic Normal Pressure Hydrocephalus: A Nationwide Retrospective Cohort Study.
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- International Journal of Medical Sciences, 2024, v. 21, n. 4, p. 656, doi. 10.7150/ijms.92032
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- Article
iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis.
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- BMC Bioinformatics, 2011, v. 12, n. Suppl 1, p. 1, doi. 10.1186/1471-2105-12-S1-S33
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- Article
Aseptic meningitis and ischemic stroke in relapsing polychondritis.
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- Clinical Rheumatology, 2006, v. 25, n. 2, p. 265, doi. 10.1007/s10067-005-1152-3
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- Article
The Antileukemic Effect of Xestoquinone, A Marine-Derived Polycyclic Quinone-Type Metabolite, Is Mediated through ROS-Induced Inhibition of HSP-90.
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- Molecules, 2021, v. 26, n. 22, p. 7037, doi. 10.3390/molecules26227037
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- Article
EfficientNet-based machine learning architecture for sleep apnea identification in clinical single-lead ECG signal data sets.
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- BioMedical Engineering OnLine, 2024, v. 23, n. 1, p. 1, doi. 10.1186/s12938-024-01252-w
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- Article
Pathway-based Screening Strategy for Multitarget Inhibitors of Diverse Proteins in Metabolic Pathways.
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- PLoS Computational Biology, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.pcbi.1003127
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- Article
Magnolol, A Novel Antagonist of Thrombin and PAR-1, Inhibits Thrombin-Induced Connective Tissue Growth Factor (CTGF) Expression in Vascular Smooth Muscle Cells and Ameliorate Pathogenesis of Restenosis in Rats.
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- Applied Sciences (2076-3417), 2020, v. 10, n. 23, p. 8729, doi. 10.3390/app10238729
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- Article
Structural Insights to the Heterotetrameric Interaction between the Vibrio parahaemolyticus PirAvp and PirBvp Toxins and Activation of the Cry-Like Pore-Forming Domain.
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- Toxins, 2019, v. 11, n. 4, p. 233, doi. 10.3390/toxins11040233
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- Article
Urolithin A exhibits a neuroprotective effect against Alzheimer's disease by inhibiting DYRK1A activity.
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- Journal of Food & Drug Analysis, 2023, v. 31, n. 2, p. 358, doi. 10.38212/2224-6614.3462
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- Article
Potent sialic acid inhibitors that target influenza A virus hemagglutinin.
- Published in:
- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87845-0
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- Publication type:
- Article
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors.
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- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-67420-9
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- Article
Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury.
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- BMC Pharmacology & Toxicology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s40360-020-0400-0
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- Article
Design of Diarylheptanoid Derivatives as Dual Inhibitors Against Class IIa Histone Deacetylase and β-amyloid Aggregation.
- Published in:
- Frontiers in Pharmacology, 2018, p. N.PAG, doi. 10.3389/fphar.2018.00708
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- Article
A Novel Dual HDAC6 and Tubulin Inhibitor, MPT0B451, Displays Anti-tumor Ability in Human Cancer Cells in Vitro and in Vivo.
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- Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00205
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- Article
Carotid Ultrasound Criteria for Detecting Intracranial Carotid Stenosis.
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- European Neurology, 2007, v. 57, n. 3, p. 156, doi. 10.1159/000098467
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- Article
Fuzzy Decision Making Approach to Identify Optimum Enzyme Targets and Drug Dosage for Remedying Presynaptic Dopamine Deficiency.
- Published in:
- PLoS ONE, 2016, v. 11, n. 10, p. 1, doi. 10.1371/journal.pone.0164589
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- Article
Exploration of anti‐leukemic effect of soft coral‐derived 13‐acetoxysarcocrassolide: Induction of apoptosis via oxidative stress as a potent inhibitor of heat shock protein 90 and topoisomerase II.
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- Kaohsiung Journal of Medical Sciences, 2023, v. 39, n. 7, p. 718, doi. 10.1002/kjm2.12678
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- Article
Anchor-based classification and type-C inhibitors for tyrosine kinases.
- Published in:
- Scientific Reports, 2015, p. 10938, doi. 10.1038/srep10938
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- Article
Accurately Identifying Cerebroarterial Stenosis from Angiography Reports Using Natural Language Processing Approaches.
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- Diagnostics (2075-4418), 2022, v. 12, n. 8, p. 1882, doi. 10.3390/diagnostics12081882
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- Article
Identification of Metabolomics Biomarkers in Extracranial Carotid Artery Stenosis.
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- Cells (2073-4409), 2022, v. 11, n. 19, p. 3022, doi. 10.3390/cells11193022
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- Article
Renal function is associated with one-month and one-year mortality in patients with intracerebral hemorrhage.
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- PLoS ONE, 2023, v. 17, n. 1, p. 1, doi. 10.1371/journal.pone.0269096
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- Article
CHA2DS2-VASc score as an independent outcome predictor in patients hospitalized with acute ischemic stroke.
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- PLoS ONE, 2022, v. 17, n. 7, p. 1, doi. 10.1371/journal.pone.0270823
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- Article
Protective DAD: A Fast Address-Acquisition Strategy for Mobile IPv6 Networks.
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- IEEE Internet Computing, 2006, v. 10, n. 6, p. 50, doi. 10.1109/MIC.2006.131
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- Article
Predicting ischemic stroke patients' prognosis changes using machine learning in a nationwide stroke registry.
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- Medical & Biological Engineering & Computing, 2024, v. 62, n. 8, p. 2343, doi. 10.1007/s11517-024-03073-4
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- Article