We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Favorable Outcomes of Elderly ABO-Incompatible Kidney Transplantation-Pilot Single Center Experience.
- Authors
Kosoku, Akihiro; Uchida, Junji; Kabei, Kazuya; Nishide, Shunji; Shimada, Hisao; Iwai, Tomoaki; Kuwabara, Nobuyuki; Naganuma, Toshihide; Maeda, Keiko; Kumada, Norihiko; Takemoto, Yoshiaki; Nakatani, Tatsuya
- Abstract
Background: The growth in the end-stage kidney disease (ESKD) population has been predominantly in the older adult population. In Japan, ABO-incompatible kidney transplantation has become an acceptable treatment option. However, few studies have been conducted on elderly ABO-incompatible kidney transplantation. Patients and Methods: Seventeen patients aged 60 years and older who received their grafts from ABO-incompatible living donors at our institution between December 2006 and September 2016 were enrolled in this study, and the outcome of these recipients was evaluated. Results: All 17 patients underwent successful kidney transplantation. Both overall patient and graft survival rates were 100, 100, and 83.3% at posttransplant 1, 3, and 5 years respectively. Six of the 17 patients (35.3%) had an episode of biopsy-proven acute cellular rejection. Two patients who developed steroid- and deoxyspergualin-resistant acute rejection required anti-human thymocyte immunoglobulin. Conclusion: ABO-incompatible kidney transplantation may be an effective radical renal replacement therapy for elderly patients with ESKD, although it could be a high-risk procedure.
- Subjects
CHRONIC kidney failure; KIDNEY transplantation; KIDNEY disease diagnosis; KIDNEY disease treatments; HEMODIALYSIS
- Publication
Urologia Internationalis, 2018, Vol 101, Issue 4, p459
- ISSN
0042-1138
- Publication type
Article
- DOI
10.1159/000492721