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- Title
Visualization of Metastatic Lung Cancer with TiNIR.
- Authors
Mun, Seul-Ki; Sim, Hyun Bo; Han, Ji Yeon; Kim, Hyeongyeong; Park, Dae-Han; Chang, Dong-Jo; Yee, Sung-Tae; Chang, Young-Tae; Kim, Jong-Jin
- Abstract
The development of efficient biomarkers and probes for monitoring and treating cancer, specifically metastatic cancer, is a critical research area that can have a significant impact on both patient outcomes and drug discovery. In this context, TiNIR has been developed to detect tumor-initiating cells (TICs), with heme oxygenase 2 (HO2) as a promising therapeutic biomarker for tumor-initiating cells. In this study, TiNIR has demonstrated its effectiveness as an in vivo metastatic lung cancer tracker, highlighting its potential as a valuable tool in cancer research and therapy. The development of innovative approaches that selectively target metastatic cancers represents a promising avenue for improving survival rates and enhancing the quality of life of cancer patients.
- Subjects
METASTASIS; LUNG cancer; DRUG discovery; HEME oxygenase; DATA visualization; DRUGGED driving; GEFITINIB
- Publication
Tomography: A Journal for Imaging Research, 2023, Vol 9, Issue 4, p1187
- ISSN
2379-1381
- Publication type
Article
- DOI
10.3390/tomography9040096