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- Title
Comparison of two rapid immunoassays for screening of hcv infection in dialysis patients.
- Authors
Swapna, S.; Anant, K. S.; P., Hema Prakash Kumari; P., Vijaya lakshmi
- Abstract
Introduction: In case of diagnosis of infectious disease, dissonant results may have serious outcomes among the patients as it causes un-necessary mental stress and tension. For appropriate diagnosis of infection as well as disease management and prevention, detection of appropriate test kit is necessary. Method: ELISA was used as gold standard for comparative evaluation. Ninety two samples were collected and processed using Elisa and two rapid immune assay test kits (HCV Tridot, FLAVI check HCV). Results: From the results, it was revealed that, out of 92 serum samples collected, male preponderance (69.5%) was seen. Taking HCV Microlisa as a standard reference test, out of 92 samples, 35.8% sero-positivity was observed. In the present study, HCV Tridot sensitivity was 96.9% and FLAVI check sensitivity was 93.9%. Conclusion: Rapid assays must be used with care and it is also significant to validate these rapid assays by testing them in a given population to evaluate the effectiveness of these assays. Atleast two rapid assays should be carried out for detecting HCV antibodies in dialysis patients as preliminary tests and should further confirmed by gold standard assay method like ELISA for accuracy.
- Subjects
HEPATITIS C diagnosis; IMMUNOASSAY; HEMODIALYSIS; PSYCHOLOGICAL stress; VIRAL antibodies
- Publication
Indian Journal of Basic & Applied Medical Research, 2017, Vol 7, Issue 1, p334
- ISSN
2250-284X
- Publication type
Article