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- Title
Evaluation of the Oral Microbiome before and after Treatments for Halitosis with Photodynamic Therapy and Probiotics—Pilot Study.
- Authors
de Barros Motta, Pamella; Gonçalves, Marcela Leticia Leal; Gallo, Juliana Maria Altavista Sagretti; Sobral, Ana Paula Taboada; Motta, Lara Jansiski; Santos, Elaine Marcílio; de Andrade, David José Casimiro; Duran, Cinthya Cosme Gutierrez; Fernandes, Kristianne Porta Santos; Mesquita-Ferrari, Raquel Agnelli; Horliana, Anna Carolina Ratto Tempestini; Bussadori, Sandra Kalil
- Abstract
Background: To compare photodynamic therapy and the use of probiotics in reducing halitosis assessed through gas chromatography and microbiome analysis. Methods: Participants aged from 18 to 25 years showing sulfide (SH2) ≥ 112 ppb on gas chromatography were selected. They were divided into four treatment groups: Group 1—Tongue Scraping; Group 2—Antimicrobial Photodynamic Therapy (aPDT); Group 3—Probiotics; and Group 4—Antimicrobial Photodynamic Therapy (aPDT) and Probiotics. The halimetry process was performed before, immediately after the treatments, and 7 days, 14 days, and 30 days after the initial collection. The collections for later microbiological analysis were made along with the halimetry for microbiome analysis. Results: Treatment with aPDT or probiotics under these experimental conditions was not able to change the bacteria present in the biofilm of the tongue. Conclusions: More research is needed to know the behavior of the oral microbiome in the presence of halitosis and the effectiveness of new treatments.
- Subjects
RESEARCH funding; PILOT projects; HUMAN microbiota; DESCRIPTIVE statistics; GAS chromatography; PRE-tests &; post-tests; TONGUE; BAD breath; PHOTODYNAMIC therapy; PROBIOTICS; COMPARATIVE studies
- Publication
Healthcare (2227-9032), 2024, Vol 12, Issue 11, p1123
- ISSN
2227-9032
- Publication type
Article
- DOI
10.3390/healthcare12111123