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- Title
1,3-oxazole derived cytisines.
- Authors
Abdurakhmanova, E.; Pil'o, S.; Kondratyuk, K.; Golovchenko, A.; Brovarets, V.
- Abstract
Reactions of 1-acylamino-2,2-dichloroacrylonitriles, diethyl 1-acylamino-2,2,2-trichloroethyl-phosphonates and 1-acylamino-2,2-dichloroethenylphosphonium salts with natural alkaloid cytisine have been studied. A series of novel multifunctional cytisine derivatives containing pharmacophore 1,3-oxazole moiety have been obtained. Composition and structure of the synthesized compounds have been confirmed by mass spectrometry and NMR spectroscopy data.
- Subjects
CHEMICAL reactions; ACYLAMINO compounds; ALKALOIDS; CYTISINE; OXAZOLES synthesis
- Publication
Russian Journal of General Chemistry, 2017, Vol 87, Issue 2, p244
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S1070363217020153