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- Title
COMPARATIVE ASSESSMENT OF THE BENEFITS OF POTASSIUM AND MAGNESIUM TRIBASIC CITRATE VERSUS TAMSULOSIN IN NEPHROLITHIASIC PATIENTS.
- Authors
PRICOP, CĂTĂLIN; PUIA, DRAGOŞ; ŞERBAN, DRAGOMIR; PERIDE, ILEANA; NICULAE, ANDREI; JINGA, VIOREL
- Abstract
Nephrolithiasis is a major health issue. Present guidelines recommend conservative treatment for calculi less than 5 mm. Over the years, various therapeutic regimens to facilitate spontaneous passage of stones have been used without reaching a consensus in this respect. We aimed to compare the efficacy of potassium and magnesium tribasic citrate which has metaphylactic indications with that of a selective alpha-blocker as medical expulsion therapy. The preliminary results of this ongoing study showed that in patients with pelvic ureteric lithiasis, the alpha-blocker-based expulsion treatment was significantly more effective than that based on potassium and magnesium tribasic citrate. As for asymptomatic lumbar ureteric lithiasis below 7 mm in diameter, the alpha-blocker and potassium and magnesium tribasic citrate treatment showed similar results.
- Subjects
CITRATES; TAMSULOSIN; TREATMENT of calculi; DRUG efficacy; ADRENERGIC alpha blockers
- Publication
Farmacia, 2018, Vol 66, Issue 2, p347
- ISSN
0014-8237
- Publication type
Article