We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cognitive Decline after Electroconvulsive Therapy Based on Different Psychiatric Disorders.
- Authors
Zandifar, Atefeh; Badrfam, Rahim; Assareh, Marzie; Hossein Ali Pahlevan; Naji, Borzooyeh
- Abstract
Objective: Electroconvulsive therapy is still a favorable method in some critical psychiatric cases after about 8 decades of its introduction. The most adverse effect of the method is the cognitive decline that affects up to 75% of patients. Therefore, getting familiar with its patterns and interfering factors may lead to the minimizing of the adverse consequences. Methodology: Seventy eight patients were chosen for ECT and entered the study through considering inclusion and exclusion criteria. The Mini Mental Status Examination was conducted 4 times before the protocol, and after the first, third and sixth sessions. The scores of this inventory and its four subtests were assessed during the protocol using the repeated measures ANOVA. In addition, the probable correlations among the scores, gender, age, and diagnoses were evaluated. Results: Although an overall significant cognitive decline was noticed during the sessions, none of the subtests could prove the significance separately. The attention and calculation subtest, and the orientation and recall subtest showed a reductive trend while the scores of registration followed a mild rising pattern. The results were independent of the variables of age, gender, and diagnoses. The most important result showed a transient amelioration of the cognitive status after the third session that turned into a final reduction. Conclusion: The cognitive decline shown by MMSE and its subtests (except the registration) is compatible with previous studies. Besides, the transient cognitive improvement after the third session could be explained by the initiation of the therapeutic effects and the remission of the disorder-induced cognitive decline before the appearance of the adverse cognitive consequences of ECT. The cognitive decline is more severe in females, probably due to the greater number of schizophrenics among male samples who suffer from a prior disorder-induced cognitive destruction.
- Subjects
ELECTROCONVULSIVE therapy; MENTAL illness; MENTAL status examination; TREATMENT effectiveness; INDEPENDENT variables
- Publication
Iranian Journal of Psychiatry & Behavioral Sciences / Progress in Psychiatry & Behavioral Sciences, 2018, p168
- ISSN
1735-8639
- Publication type
Article