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- Title
Rabies Virus-Neutralizing Antibodies in Free-Ranging Invasive Wild Boars (Sus scrofa) from Brazil.
- Authors
Perin, Patricia Parreira; Turmina, Talita; Arias-Pacheco, Carmen Andrea; Gomes, Jonathan Silvestre; Andrade, Lívia de Oliveira; Zolla, Natália de Oliveira; Mendonça, Talita Oliveira; Oliveira, Wilson Junior; Fahl, Willian de Oliveira; Scheffer, Karin Correa; Cunha Neto, Rene dos Santos; Chierato, Maria Eduarda Rodrigues; Mori, Enio; Felicio, Artur Luiz de Almeida; Haga, Guilherme Shin Iwamoto; Guido, Maria Carolina; Barrochelo, Luiz Henrique; Marcos, Affonso dos Santos; Lux Hoppe, Estevam Guilherme
- Abstract
Rabies, one of the most lethal global zoonoses, affects all mammals. It remains circulating worldwide in sylvatic cycles through terrestrial and airborne reservoirs, and in Brazil, bats are currently the main reservoirs and source of transmission. Wild boars, an important invasive alien species in Brazil, are a proven food source for hematophagous bats and may participate in the Brazilian sylvatic cycle of rabies. We evaluated the presence of this pathogen in hunted wild boars from the São Paulo state using histopathology, the direct fluorescent antibody test (DFA), viral isolation in cell culture (VICC), the rapid fluorescent focus inhibition test (RFFIT), and quantitative reverse transcription polymerase chain reaction (RT-qPCR). The results of histopathological, DFA, VICC, and RT-qPCR analysis were negative for all samples; seven serum samples tested positive in the RFFIT, and titers ranged from 0.13 IU/mL to 0.5 IU/mL. The presence of rabies virus-neutralizing antibodies in the studied wild boars suggests the circulation of the virus in these animals. Educative actions directed at hunters should include information on the prevention of this important zoonosis.
- Subjects
BRAZIL; SAO Paulo (Brazil : State); RABIES virus; WILD boar; RABIES; REVERSE transcriptase polymerase chain reaction; INTRODUCED species
- Publication
Pathogens, 2024, Vol 13, Issue 4, p303
- ISSN
2076-0817
- Publication type
Article
- DOI
10.3390/pathogens13040303