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- Title
Open-closed switching of synthetic tubular pores.
- Authors
Kim, Yongju; Kang, Jiheong; Shen, Bowen; Wang, Yanqiu; He, Ying; Lee, Myongsoo
- Abstract
While encouraging progress has been made on switchable nanopores to mimic biological channels and pores, it remains a great challenge to realize long tubular pores with a dynamic open-closed motion. Here we report μm-long, dynamic tubular pores that undergo rapid switching between open and closed states in response to a thermal signal in water. The tubular walls consist of laterally associated primary fibrils stacked from disc-shaped molecules in which the discs readily tilt by means of thermally regulated dehydration of the oligoether chains placed on the wall surfaces. Notably, this pore switching mediates a controlled water-pumping catalytic action for the dehydrative cyclization of adenosine monophosphate to produce metabolically active cyclic adenosine monophosphate. We believe that our work may allow the creation of a variety of dynamic pore structures with complex functions arising from open-closed motion.
- Subjects
SWITCHING circuits; NANOPORES; ADENOSINE monophosphate; CYCLIC adenylic acid; SYNTHETIC pores
- Publication
Scientific Reports, 2015, p8650
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/ncomms9650