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- Title
Rifampicin treatment of canine multidrug‐resistant meticillin‐resistant staphylococcal pyoderma: A retrospective study of 51 cases.
- Authors
Harbour, Lydia; Schick, Anthea; Mount, Rebecca; White, Amelia
- Abstract
Three dogs that had a good response to initial RFP treatment had a second course of RFP within three to five months as a consequence of recurrence of infection. B Background - b Rifampicin (RFP) is a potential treatment for canine multidrug-resistant (MDR) meticillin-resistant staphylococci (MRS), yet the use of lower doses based on recent MIC data has not been evaluated I in vivo i . Future prospective studies in dogs are needed to determine the prevalence and rapidity of RFP resistance upon initial drug exposure and the potential for biological and virulence changes in RPF-resistant staphylococci. SP 21 sp It is important to note that most dogs in this study had some form of concurrent topical antimicrobial therapy, which is critically important in the age of antimicrobial resistance. Only one dog had a repeat C&S performed showing MRSP sensitive to RFP, while all three dogs had a good treatment response with the repeat course.
- Subjects
RIFAMPIN; ALANINE aminotransferase; ANTIBIOTICS; DRUG side effects; DRUG formularies; TERMINATION of treatment; STAPHYLOCOCCUS aureus infections; METHICILLIN-resistant staphylococcus aureus
- Publication
Veterinary Dermatology, 2022, Vol 33, Issue 5, p384
- ISSN
0959-4493
- Publication type
Article
- DOI
10.1111/vde.13105