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- Title
Intra-Host Diversity of Dengue Virus in Mosquito Vectors.
- Authors
Bifani, Amanda Makha; Siriphanitchakorn, Tanamas; Choy, Milly M.
- Abstract
Dengue virus (DENV) is the most common arbovirus, causing a significant burden on both the economy and global healthcare systems. The virus is transmitted by Aedes species of mosquitoes as a swarm of closely related virus genomes, collectively referred to as a quasispecies. The level of genomic diversity within this quasispecies varies as DENV moves through various ecological niches within its transmission cycle. Here, the factors that influence the level of DENV quasispecies diversity during the course of infection in the mosquito vectors are reviewed.
- Subjects
MOSQUITO vectors; DENGUE viruses; VIRUS diversity; VIRAL genomes; ECOLOGICAL niche; SPECIES diversity
- Publication
Frontiers in Cellular & Infection Microbiology, 2022, Vol 12, p1
- ISSN
2235-2988
- Publication type
Article
- DOI
10.3389/fcimb.2022.888804