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- Title
Efficacy of dietary treatments for epilepsy.
- Authors
Neal, E. G.; Cross, J. H.
- Abstract
The ketogenic diet (KD) is a high fat, restricted carbohydrate regime that has been used as a treatment for seizures since the 1920s, when it was designed to induce a similar metabolic response to fasting. A modification of this early classical version of the KD was introduced in the 1970s using medium chain triglycerides as an alternative fat source. More recently, two alternative, less-restrictive dietary treatments have been developed: the modified Atkins diet and the low glycaemic index diet. There are many case reports and observational studies reporting successful use of the KD, and a growing number of studies reporting similar success with the modified Atkins protocol. A recent randomised controlled trial has shown a significant benefit of the KD compared to no change in treatment. The use of these dietary therapies in the UK is supported by literature evidence, although often is limited by a lack of resources; increasing awareness and knowledge is fundamental to ensure availability for those individuals with intractable epilepsy who may benefit from them.
- Subjects
EPILEPSY; DIET in disease; ACETONEMIA; BRAIN diseases; SEIZURES (Medicine); DIETETICS; DIET therapy; FASTING; RANDOMIZED controlled trials
- Publication
Journal of Human Nutrition & Dietetics, 2010, Vol 23, Issue 2, p113
- ISSN
0952-3871
- Publication type
Article
- DOI
10.1111/j.1365-277X.2010.01043.x