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- Title
Limbal-Conjunctival vs Conjunctival Autograft Transplant for Recurrent Pterygia: A Prospective Randomized Controlled Trial.
- Authors
Al Fayez, Mashhoor F
- Abstract
To compare the safety and efficacy of limbal-conjunctival vs conjunctival autograft transplant for treating recurrent pterygia.~Objective~Objective~In a randomized, prospective, parallel-group clinical trial, 224 patients with advanced recurrent pterygia underwent free conjunctival autograft transplant (112 eyes) or limbal-conjunctival autograft transplant (112 eyes). Two hundred five patients completed the follow-up (100 eyes from the conjunctival autograft group and 105 eyes from the limbal-conjunctival autograft group).~Methods~Methods~Recurrence of pterygium, with complications as the secondary outcome measure (ie, signs of limbal stem cell deficiency).~Main Outcome Measures~Methods~With a mean follow-up of 62 (range, 36-96) months, 10 patients (10.0%) in the conjunctival autograft group and 1 patient (1.0%) in the limbal-conjunctival autograft group developed recurrence. No signs of limbal stem cell deficiency were observed during follow-up.~Results~Results~Limbal-conjunctival transplant is safe and more effective than free conjunctival transplant in preventing recurrence after excision of recurrent pterygia (P = .004).~Conclusion~Conclusions~Limbal-conjunctival autografts could be a favored option for managing advanced recurrent pterygia in young high-risk patients.~Application To Clinical Practice~Conclusions
- Publication
JAMA Ophthalmology, 2013, Vol 131, Issue 1, p11
- ISSN
2168-6165
- Publication type
Journal Article
- DOI
10.1001/archophthalmol.2012.2599