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- Title
Papulonodular mucinosis in the setting of systemic lupus erythematosus – a diagnostic conundrum.
- Authors
Esteves, Mariana; Gomes, Nuno; Nogueira, Ana; Azevedo, Filomena
- Abstract
Dear Editor, Cutaneous mucinoses are characterized by an aberrant deposition of acid glycosaminoglycans in the dermis and within hair follicles, which generally represents a primary process.1,2 While it is also a common histologic finding in connective tissue diseases (such as lupus erythematosus [LE], scleroderma, or dermatomyositis), its presence in quantities large enough to form clinically detectable lesions is unusual.2-4 A 43-year-old female presented with a 3-month history of multiple firm, skin-colored papulonodules on the neck, upper limbs, and trunk (Fig. At this point, the patient fulfilled criteria for systemic LE (SLE); we therefore reclassified the dermatosis as papulonodular mucinosis (PNM) in the setting of SLE. Papulonodular mucinosis: an unusual presenting feature of systemic lupus erythematosus.
- Subjects
MONOCLONAL gammopathies; LUPUS erythematosus; SYSTEMIC lupus erythematosus; ANTIBODY titer; ACID deposition
- Publication
International Journal of Dermatology, 2020, Vol 59, Issue 12, pe447
- ISSN
0011-9059
- Publication type
Article
- DOI
10.1111/ijd.15171