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The IgG4 hinge with CD28 transmembrane domain improves V<sub>H</sub>H-based CAR T cells targeting a membrane-distal epitope of GPC1 in pancreatic cancer.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37616-4
By:
- Li, Nan;
- Quan, Alex;
- Li, Dan;
- Pan, Jiajia;
- Ren, Hua;
- Hoeltzel, Gerard;
- de Val, Natalia;
- Ashworth, Dana;
- Ni, Weiming;
- Zhou, Jing;
- Mackay, Sean;
- Hewitt, Stephen M.;
- Cachau, Raul;
- Ho, Mitchell
Publication type:
Article
Tips and Tricks for Managing an EM Lab.
Published in:
Microscopy & Microanalysis, 2024, v. 30, p. 1, doi. 10.1093/mam/ozae044.1104
By:
- Hsia, Ru-Ching;
- Martens, Richard;
- Val, Natalia de;
- Cohen-Gould, Lee;
- Baluch, D Page
Publication type:
Article
Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage.
Published in:
Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01631
By:
- Yang, Lifei;
- Sharma, Shailendra Kumar;
- Cottrell, Christopher;
- Guenaga, Javier;
- Tran, Karen;
- Wilson, Richard;
- Behrens, Anna-Janina;
- Crispin, Max;
- de Val, Natalia;
- Wyatt, Richard T.
Publication type:
Article
Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies.
Published in:
Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01116
By:
- Bale, Shridhar;
- Martiné, Alexandra;
- Wilson, Richard;
- Behrens, Anna-Janina;
- Le Fourn, Valérie;
- de Val, Natalia;
- Sharma, Shailendra K.;
- Tran, Karen;
- Torres, Jonathan L.;
- Girod, Pierre-Alain;
- Ward, Andrew B.;
- Crispin, Max;
- Wyatt, Richard T.
Publication type:
Article
Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
Published in:
PLoS Pathogens, 2018, v. 14, n. 5, p. 1, doi. 10.1371/journal.ppat.1006986
By:
- Schiffner, Torben;
- Pallesen, Jesper;
- Russell, Rebecca A.;
- Dodd, Jonathan;
- de Val, Natalia;
- LaBranche, Celia C.;
- Montefiori, David;
- Tomaras, Georgia D.;
- Shen, Xiaoying;
- Harris, Scarlett L.;
- Moghaddam, Amin E.;
- Kalyuzhniy, Oleksandr;
- Sanders, Rogier W.;
- McCoy, Laura E.;
- Moore, John P.;
- Ward, Andrew B.;
- Sattentau, Quentin J.
Publication type:
Article
Author Correction: Cryo-EM structure of the bacterial Ton motor subcomplex ExbB–ExbD provides information on structure and stoichiometry.
Published in:
2020
By:
- Celia, Herve;
- Botos, Istvan;
- Ni, Xiaodan;
- Fox, Tara;
- de Val, Natalia;
- Lloubes, Roland;
- Jiang, Jiansen;
- Buchanan, Susan K.
Publication type:
Correction Notice
Development of Neutralization Breadth against Diverse HIV‐1 by Increasing Ab–Ag Interface on V2.
Published in:
Advanced Science, 2022, v. 9, n. 15, p. 1, doi. 10.1002/advs.202200063
By:
- Gao, Nan;
- Gai, Yanxin;
- Meng, Lina;
- Wang, Chu;
- Wang, Wei;
- Li, Xiaojun;
- Gu, Tiejun;
- Louder, Mark K.;
- Doria‐Rose, Nicole A.;
- Wiehe, Kevin;
- Nazzari, Alexandra F.;
- Olia, Adam S.;
- Gorman, Jason;
- Rawi, Reda;
- Wu, Wenmin;
- Smith, Clayton;
- Khant, Htet;
- de Val, Natalia;
- Yu, Bin;
- Luo, Junhong
Publication type:
Article
Transcriptome-based molecular staging of human stem cellderived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal.
Published in:
Molecular Vision, 2019, v. 25, p. 663
By:
- Kaya, Koray D.;
- Chen, Holly Y.;
- Brooks, Matthew J.;
- Kelley, Ryan A.;
- Hiroko Shimada;
- Kunio Nagashima;
- de Val, Natalia;
- Drinnan, Charles T.;
- Gieser, Linn;
- Kruczek, Kamil;
- Erceg, Slaven;
- Tiansen Li;
- Lukovic, Dunja;
- Adlakha, Yogita K.;
- Welby, Emily;
- Swaroop, Anand
Publication type:
Article
Uncleaved prefusion-optimized gp140 trimers derived from analysis of HIV-1 envelope metastability.
Published in:
Nature Communications, 2016, v. 7, n. 6, p. 12040, doi. 10.1038/ncomms12040
By:
- Kong, Leopold;
- He, Linling;
- de Val, Natalia;
- Vora, Nemil;
- Morris, Charles D.;
- Azadnia, Parisa;
- Sok, Devin;
- Zhou, Bin;
- Burton, Dennis R.;
- Ward, Andrew B.;
- Wilson, Ian A.;
- Zhu, Jiang
Publication type:
Article
Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles.
Published in:
Nature Communications, 2016, v. 7, n. 6, p. 12041, doi. 10.1038/ncomms12041
By:
- He, Linling;
- de Val, Natalia;
- Morris, Charles D.;
- Vora, Nemil;
- Thinnes, Therese C.;
- Kong, Leopold;
- Azadnia, Parisa;
- Sok, Devin;
- Zhou, Bin;
- Burton, Dennis R.;
- Wilson, Ian A;
- Nemazee, David;
- Ward, Andrew B.;
- Zhu, Jiang
Publication type:
Article
Development of Neutralizing Antibodies against Zika Virus Based on Its Envelope Protein Structure.
Published in:
Virologica Sinica (16740769), 2019, v. 34, n. 2, p. 168, doi. 10.1007/s12250-019-00093-5
By:
- Yang, Chunpeng;
- Gong, Rui;
- de Val, Natalia
Publication type:
Article
Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies.
Published in:
PLoS Pathogens, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.ppat.1005767
By:
- Feng, Yu;
- Tran, Karen;
- Bale, Shridhar;
- Kumar, Shailendra;
- Guenaga, Javier;
- Wilson, Richard;
- de Val, Natalia;
- Arendt, Heather;
- DeStefano, Joanne;
- Ward, Andrew B.;
- Wyatt, Richard T.
Publication type:
Article
Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties.
Published in:
PLoS Pathogens, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.ppat.1004570
By:
- Guenaga, Javier;
- de Val, Natalia;
- Tran, Karen;
- Feng, Yu;
- Satchwell, Karen;
- Ward, Andrew B.;
- Wyatt, Richard T.
Publication type:
Article
Murine Anti-vaccinia Virus D8 Antibodies Target Different Epitopes and Differ in Their Ability to Block D8 Binding to CS-E.
Published in:
PLoS Pathogens, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.ppat.1004495
By:
- Matho, Michael H.;
- de Val, Natalia;
- Miller, Gregory M.;
- Brown, Joshua;
- Schlossman, Andrew;
- Meng, Xiangzhi;
- Crotty, Shane;
- Peters, Bjoern;
- Xiang, Yan;
- Hsieh-Wilson, Linda C.;
- Ward, Andrew B.;
- Zajonc, Dirk M.
Publication type:
Article
A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies.
Published in:
PLoS Pathogens, 2013, v. 9, n. 9, p. 1, doi. 10.1371/journal.ppat.1003618
By:
- Sanders, Rogier W.;
- Derking, Ronald;
- Cupo, Albert;
- Julien, Jean-Philippe;
- Yasmeen, Anila;
- de Val, Natalia;
- Kim, Helen J.;
- Blattner, Claudia;
- de la Peña, Alba Torrents;
- Korzun, Jacob;
- Golabek, Michael;
- de los Reyes, Kevin;
- Ketas, Thomas J.;
- van Gils, Marit J.;
- King, C. Richter;
- Wilson, Ian A.;
- Ward, Andrew B.;
- Klasse, P. J.;
- Moore, John P.
Publication type:
Article
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.83205
By:
- Chen, Holly Y.;
- Swaroop, Manju;
- Papal, Samantha;
- Mondal, Anupam K.;
- Hyun Beom Song;
- Campello, Laura;
- Tawa, Gregory J.;
- Regent, Florian;
- Hiroko Shimada;
- Kunio Nagashima;
- de Val, Natalia;
- Jacobson, Samuel G.;
- Wei Zheng;
- Swaroop, Anand
Publication type:
Article
Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01025
By:
- Linling He;
- Xiaohe Lin;
- de Val, Natalia;
- Saye-Francisco, Karen L.;
- Mann, Colin J.;
- Augst, Ryan;
- Morris, Charles D.;
- Azadnia, Parisa;
- Bin Zhou;
- Sok, Devin;
- Ozorowski, Gabriel;
- Ward, Andrew B.;
- Burton, Dennis R.;
- Jiang Zhu
Publication type:
Article
Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer.
Published in:
Science Signaling, 2021, v. 14, n. 664, p. 1, doi. 10.1126/scisignal.abc4436
By:
- Crooks, Daniel R.;
- Maio, Nunziata;
- Lang, Martin;
- Ricketts, Christopher J.;
- Vocke, Cathy D.;
- Gurram, Sandeep;
- Turan, Sevilay;
- Kim, Yun-Young;
- Cawthon, G. Mariah;
- Sohelian, Ferri;
- De Val, Natalia;
- Pfeiffer, Ruth M.;
- Jailwala, Parthav;
- Tandon, Mayank;
- Tran, Bao;
- Fan, Teresa W.-M.;
- Lane, Andrew N.;
- Ried, Thomas;
- Wangsa, Darawalee;
- Malayeri, Ashkan A.
Publication type:
Article
Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.
Published in:
PLoS Pathogens, 2017, v. 13, n. 9, p. 1, doi. 10.1371/journal.ppat.1006614
By:
- Dubrovskaya, Viktoriya;
- Guenaga, Javier;
- de Val, Natalia;
- Wilson, Richard;
- Feng, Yu;
- Movsesyan, Arlette;
- Karlsson Hedestam, Gunilla B.;
- Ward, Andrew B.;
- Wyatt, Richard T.
Publication type:
Article
EPR Studies of Recombinant Horse L-Chain Apoferritin and its Mutant (E 53,56,57,60 Q) with Haemin.
Published in:
BioMetals, 2007, v. 20, n. 1, p. 21, doi. 10.1007/s10534-006-9010-6
By:
- Natalia de Val;
- Wilfred Hagen;
- Robert Crichton
Publication type:
Article
Cryo-EM structure of the bacterial Ton motor subcomplex ExbB–ExbD provides information on structure and stoichiometry.
Published in:
Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0604-2
By:
- Celia, Herve;
- Botos, Istvan;
- Ni, Xiaodan;
- Fox, Tara;
- De Val, Natalia;
- Lloubes, Roland;
- Jiang, Jiansen;
- Buchanan, Susan K.
Publication type:
Article
Zika Virus-Induced Neuronal Apoptosis via Increased Mitochondrial Fragmentation.
Published in:
Frontiers in Microbiology, 2020, v. 11, p. N.PAG, doi. 10.3389/fmicb.2020.598203
By:
- Yang, Shu;
- Gorshkov, Kirill;
- Lee, Emily M.;
- Xu, Miao;
- Cheng, Yu-Shan;
- Sun, Nuo;
- Soheilian, Ferri;
- de Val, Natalia;
- Ming, Guoli;
- Song, Hongjun;
- Tang, Hengli;
- Zheng, Wei
Publication type:
Article
Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04272-y
By:
- Sarkar, Anita;
- Bale, Shridhar;
- Behrens, Anna-Janina;
- Kumar, Sonu;
- Sharma, Shailendra Kumar;
- de Val, Natalia;
- Pallesen, Jesper;
- Irimia, Adriana;
- Diwanji, Devan C.;
- Stanfield, Robyn L.;
- Ward, Andrew B.;
- Crispin, Max;
- Wyatt, Richard T.;
- Wilson, Ian A.
Publication type:
Article
Structure-based design of native-like HIV-1 envelope trimers to silence non-neutralizing epitopes and eliminate CD4 binding.
Published in:
Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-01549-6
By:
- Kulp, Daniel W.;
- Steichen, Jon M.;
- Pauthner, Matthias;
- Xiaozhen Hu;
- Schiffner, Torben;
- Liguori, Alessia;
- Cottrell, Christopher A.;
- Havenar-Daughton, Colin;
- Ozorowski, Gabriel;
- Georgeson, Erik;
- Kalyuzhniy, Oleksandr;
- Willis, Jordan R.;
- Kubitz, Michael;
- Adachi, Yumiko;
- Reiss, Samantha M.;
- Shin, Mia;
- de Val, Natalia;
- Ward, Andrew B.;
- Crotty, Shane;
- Burton, Dennis R.
Publication type:
Article
Mass spectrometry studies of demetallation of haemin by recombinant horse L chain apoferritin and its mutant (E 53,56,57,60 Q)
Published in:
FEBS Letters, 2006, v. 580, n. 26, p. 6275, doi. 10.1016/j.febslet.2006.10.034
By:
- de Val, Natalia;
- Herschbach, Haiko;
- Potier, Noëlle;
- Dorsselaer, Alain Van;
- Crichton, Robert R.
Publication type:
Article
IDH1 mutations induce organelle defects via dysregulated phospholipids.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20752-6
By:
- Lita, Adrian;
- Pliss, Artem;
- Kuzmin, Andrey;
- Yamasaki, Tomohiro;
- Zhang, Lumin;
- Dowdy, Tyrone;
- Burks, Christina;
- de Val, Natalia;
- Celiku, Orieta;
- Ruiz-Rodado, Victor;
- Nicoli, Elena-Raluca;
- Kruhlak, Michael;
- Andresson, Thorkell;
- Das, Sudipto;
- Yang, Chunzhang;
- Schmitt, Rebecca;
- Herold-Mende, Christel;
- Gilbert, Mark R.;
- Prasad, Paras N.;
- Larion, Mioara
Publication type:
Article

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