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- Title
Risk Factors for Overdose in Young People Who Received Substance Use Disorder Treatment.
- Authors
Yule, Amy M.; Carrellas, Nicholas W.; DiSalvo, Maura; Lyons, Rachael M.; McKowen, James W.; Nargiso, Jessica E.; Bergman, Brandon G.; Kelly, John F.; Wilens, Timothy E.
- Abstract
<bold>Background and Objectives: </bold>To identify substance and psychiatric predictors of overdose (OD) in young people with substance use disorders (SUDs) who received treatment.<bold>Methods: </bold>We conducted a retrospective review of consecutive medical records of young people who were evaluated in a SUD program between 2012 and 2013 and received treatment. An independent group of patients from the same program who received treatment and had a fatal OD were also included in the sample. OD was defined as substance use associated with a significant impairment in level of consciousness without intention of self-harm, or an ingestion of a substance that was reported as a suicide attempt. t Tests, Pearson's χ2 , and Fisher's exact tests were performed to identify predictors of OD after receiving treatment.<bold>Results: </bold>After initial evaluation, 127 out of 200 patients followed up for treatment and were included in the sample. Ten (8%) of these patients had a nonfatal OD. Nine patients who received treatment and had a fatal OD were also identified. The sample's mean age was 20.2 ± 2.8 years. Compared with those without OD, those with OD were more likely to have a history of intravenous drug use (odds ratio [OR]: 36.5, P < .001) and mood disorder not otherwise specified (OR: 4.51, P = .01).<bold>Discussion and Conclusions: </bold>Intravenous drug use and mood dysregulation increased risk for OD in young people who received SUD treatment.<bold>Scientific Significance: </bold>It is important to identify clinically relevant risk factors for OD specific to young people in SUD treatment due to the risk for death associated with OD. (Am J Addict 2019;28:382-389).
- Subjects
SUBSTANCE-induced disorders; YOUTH; DISEASE risk factors; FISHER exact test; SUBSTANCE abuse &; psychology; INTRAVENOUS drug abuse; AFFECTIVE disorders; COMPARATIVE studies; DRUG overdose; RESEARCH methodology; MEDICAL cooperation; RESEARCH; SUBSTANCE abuse; SUICIDAL behavior; EVALUATION research; RETROSPECTIVE studies; DISEASE complications
- Publication
American Journal on Addictions, 2019, Vol 28, Issue 5, p382
- ISSN
1055-0496
- Publication type
journal article
- DOI
10.1111/ajad.12938