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- Title
ANTIFUNGAL EFFICACY OF MYRTUS COMMUNIS LINN. EXTRACT AGAINST CANDIDA SP. AND ASPERGILLUS SP.
- Authors
Erfani-Nejad, Maryam; Sadeghi-Nejad, Batool; Nanaeie, Sedigheh; Zarrin, Majid; Mahmoudabadi, Ali Zarei
- Abstract
Introduction and Objectives: Myrtus communis Linn. (Family, Myrtaceae) is an aromatic evergreen perennial shrub or small tree, 1.8-2. 4m in height with small foliage and deep fissured bark. It is native to widespread in the Mediterranean region. Use of herbal medicines in Asia has been used for long time. The aim of this survey was the in vitro antifungal activity of the Ethanolic extracts of Myrtus communis leaves against strains of Candida sp. such as Candida albicans, C. glabrata, C. tropicalis and three species of Aspergillus including Aspergillus niger, A. flavus and A. terreus. Materials and Methods: The ethnologic extract of myrtle leaves was prepared by maceration method and Minimal Inhibitory Concentration (MIC) of M. communis leaves extract was determined by agar-well diffusion assay. Amphotericin B and clotrimazole were used as the positive control in this experiment. Results: The minimal inhibitory concentration (MICs) values of M. communis leaves extract ranged from 0. 625-5.0μg/μl and 5-20μg/μl against tested Candida sp. and Aspergillus sp. respectively. Conclusion: Results revealed that the ethnologic extracts of M. communis have been antifungal potency against both pathogenic tested fungi and it can be used as natural antifungal agent.
- Subjects
MEDITERRANEAN Region; MYRTLE (Plants); ASPERGILLUS; PLANT extracts; ASPERGILLUS niger; MICROBIAL sensitivity tests; AMPHOTERICIN B
- Publication
Jundishapur Journal of Microbiology, 2013, p15
- ISSN
2008-3645
- Publication type
Article