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- Title
Foetal aortic valvuloplasty: experience of five cases.
- Authors
Marantz, Pablo; Aiello, Horacio; Grinenco, Sofía; Izbizky, Gustavo; Peña, Gabriela; Trentacoste, Luis; Granja, Miguel; Otaño, Lucas
- Abstract
ObjectivesFoetal aortic valvuloplasty has been proposed as a strategy to improve left heart growth and function in foetuses with severe aortic stenosis at risk of progression to hypoplastic left heart syndrome. We report our experience with this intervention.Methods and resultsBetween 2005 and 2010, five foetuses with aortic stenosis and at risk of progression to hypoplastic left heart syndrome underwent ultrasound-guided percutaneous foetal aortic valvuloplasty. There were no associated maternal complications or foetal demise. In one case, the pregnancy was terminated a couple of weeks after the intervention, one foetus evolved to hypoplastic left heart syndrome, and three did not.ConclusionsFoetal aortic valvuloplasty seems to be a safe and feasible procedure. It has been reported that it has the potential to prevent progression to hypoplastic left heart syndrome in selected foetuses with severe aortic stenosis. Further investigation regarding physiological and clinical aspects of this disease both prenatally and postnatally will probably allow to improve therapeutic strategies and clinical outcome.
- Subjects
PERCUTANEOUS balloon valvuloplasty; AORTIC stenosis; HYPOPLASTIC left heart syndrome; MATERNAL health; FETAL ultrasonic imaging; CONGENITAL heart disease; DISEASE progression
- Publication
Cardiology in the Young, 2013, Vol 23, Issue 5, p675
- ISSN
1047-9511
- Publication type
Article
- DOI
10.1017/S104795111200176X