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- Title
POTENTIAL OF ROSEMARY OIL TO BE USED IN DRUG-RESISTANT INFECTIONS.
- Authors
Luqman, Suaib; Dwivedi, Gaurav R.; Darokar, Mahendra P.; Kalra, Alok; Khanuja, Suman P. S.
- Abstract
Objective • To evaluate the antimicrobial activity potential of the essential oil of rosemary specifically for its efficacy against the drug-resistant mutants of Mycobacterium smegmatis, Escherichia coli, and Candida albicans. Method • Antibacterial, antifungal, and drug resistance—modifying activity was evaluated both qualitatively and quantitatively following disc diffusion and broth dilution assay procedures. Results • The rosemary essential oil was found to be more active against the gram-positive pathogenic bacteria except E faecalis and drug-resistant mutants of E coli, compared to gram-negative bacteria. Similarly, it was found to be more active toward non-filamentous, filamentous, dermatophytic pathogenic fungi and drug-resistant mutants of Candida albicans. Conclusion • Our findings suggest that characterization and isolation of the active compound(s) from the rosemary oil may be useful in counteracting gram-positive bacterial, fungal, and drug-resistant infections.
- Subjects
ANTI-infective agents; ROSEMARY; MEDICINAL plants; DRUG resistance in microorganisms; EFFECT of drugs on microorganisms; MYCOBACTERIAL diseases
- Publication
Alternative Therapies in Health & Medicine, 2007, Vol 13, Issue 5, p54
- ISSN
1078-6791
- Publication type
Article