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- Title
P224 - MEASUREMENTS OF IODINE IN 24-H, FIRST MORNING AND SECOND MORNING URINE SAMPLES.
- Authors
YİLMAZ, Gulsen; FİDANCİ, Vildan; YUCEL, Dogan
- Abstract
Introduction: An important but often disregarded methodological aspect is the type and quality of the urine sample in which the determinations are made. Although 24 h urine collections are the ideal for determining 24 h urinary excretion of analytes, spot urine samples are preferred because of its easy use. We aimed to compare iodine concentrations of 24-h, first morning and second morning urine samples. Material and methods: A total of 120 24-h, first morning and second morning urine samples were collected from members of the hospital staff and relatives. Volumes of each sample were measured and recorded. Urine samples were frozen within 2 h of collection and stored at -80 °C until the measurement day. Iodine concentrations of three different urine samples were measured simultaneously. Results: Mean iodine concentrations were 171 ±32 mg/dL for first morning urine, 165±34 mg/dL for second morning urine, 164±33 mg/dL for 24 h urine samples. Differences in the mean values for the sample types were compared by paired t-test and found as statistically not significant (p>0.05). Discussion: As spot urine samples can be obtained easily, spot urine samples become the preferred sample type in clinical laboratories compared with 24 hour urine samples. Our data suggest that spot urine samples especially second morning urine can be used for iodine measurements for clinical or epidemiological studies.
- Subjects
IODINE; HALOGENS; URINE; BODY fluids; IODINE compounds
- Publication
Turkish Journal of Biochemistry / Turk Biyokimya Dergisi, 2012, Vol 37, Issue S1, p365
- ISSN
0250-4685
- Publication type
Article