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A multifaceted educational intervention improved anti-infectious measures but had no effect on mortality in patients with severe sepsis.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07915-9
By:
- Schwarzkopf, Daniel;
- Matthaeus-Kraemer, Claudia Tanja;
- Thomas-Rüddel, Daniel O.;
- Rüddel, Hendrik;
- Poidinger, Bernhard;
- Bach, Friedhelm;
- Gerlach, Herwig;
- Gründling, Matthias;
- Lindner, Matthias;
- Scheer, Christian;
- Simon, Philipp;
- Weiss, Manfred;
- Reinhart, Konrad;
- Bloos, Frank;
- MEDUSA study group;
- Marx, Gernot;
- Schindler, Achim;
- Schürholz, Tobias;
- Schlegel‑Höfner, Heike;
- Lehmann, Gunther
Publication type:
Article
Anti-Infective and Anti-Inflammatory Mode of Action of Peptide 19-2.5.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 3, p. 1465, doi. 10.3390/ijms22031465
By:
- Heinbockel, Lena;
- Weindl, Günther;
- Correa, Wilmar;
- Brandenburg, Julius;
- Reiling, Norbert;
- Wiesmüller, Karl-Heinz;
- Schürholz, Tobias;
- Gutsmann, Thomas;
- Martinez de Tejada, Guillermo;
- Mauss, Karl;
- Brandenburg, Klaus;
- Franzyk, Henrik
Publication type:
Article
A case series on the value of tau and neurofilament protein levels to predict and detect delirium in cardiac surgery patients.
Published in:
Biomedical Papers of the Medical Faculty of Palacky University in Olomouc, 2019, v. 163, n. 3, p. 241, doi. 10.5507/bp.2019.043
By:
- Saller, Thomas;
- Petzold, Axel;
- Zetterberg, Henrik;
- Kuhle, Jens;
- Chappell, Daniel;
- von Dossow, Vera;
- Klawitter, Felix;
- Schürholz, Tobias;
- Hagl, Christian;
- Reuter, Daniel A.;
- Zwissler, Bernhard;
- Ehler, Johannes
Publication type:
Article
Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides.
Published in:
Scientific Reports, 2015, p. 14292, doi. 10.1038/srep14292
By:
- de Tejada, Guillermo Martinez;
- Heinbockel, Lena;
- Ferrer-Espada, Raquel;
- Heine, Holger;
- Alexander, Christian;
- Bárcena-Varela, Sergio;
- Goldmann, Torsten;
- Correa, Wilmar;
- Wiesmüller, Karl-Heinz;
- Gisch, Nicolas;
- Sánchez-Gómez, Susana;
- Fukuoka, Satoshi;
- Schürholz, Tobias;
- Gutsmann, Thomas;
- Brandenburg, Klaus
Publication type:
Article
Therapeutical Administration of Peptide Pep19-2.5 and Ibuprofen Reduces Inflammation and Prevents Lethal Sepsis.
Published in:
PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0133291
By:
- Heinbockel, Lena;
- Marwitz, Sebastian;
- Barcena Varela, Sergio;
- Ferrer-Espada, Raquel;
- Reiling, Norbert;
- Goldmann, Torsten;
- Gutsmann, Thomas;
- Mier, Walter;
- Schürholz, Tobias;
- Drömann, Daniel;
- Brandenburg, Klaus;
- Martinez de Tejada, Guillermo
Publication type:
Article
CONSORT Item Reporting Quality in the Top Ten Ranked Journals of Critical Care Medicine in 2011: A Retrospective Analysis.
Published in:
PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0128061
By:
- Stevanovic, Ana;
- Schmitz, Sabine;
- Rossaint, Rolf;
- Schürholz, Tobias;
- Coburn, Mark
Publication type:
Article
Antibacterial action of synthetic antilipopolysaccharide peptides (SALP) involves neutralization of both membrane‐bound and free toxins.
Published in:
FEBS Journal, 2019, v. 286, n. 8, p. 1576, doi. 10.1111/febs.14805
By:
- Correa, Wilmar;
- Heinbockel, Lena;
- Behrends, Jochen;
- Kaconis, Yani;
- Barcena‐Varela, Sergio;
- Gutsmann, Thomas;
- Mauss, Karl;
- Schürholz, Tobias;
- Schromm, Andra B.;
- Martinez de Tejada, Guillermo;
- Brandenburg, Klaus
Publication type:
Article
The synthetic LPS binding peptide 19-2.5 interferes with clotting and prevents degradation of high molecular weight kininogen in plasma.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-64155-5
By:
- Köhler, Juliane;
- Ehler, Johannes;
- Kreikemeyer, Bernd;
- Bajorath, Rika;
- Schürholz, Tobias;
- Oehmcke-Hecht, Sonja
Publication type:
Article
Effect of a multifaceted educational intervention for anti-infectious measures on sepsis mortality: a cluster randomized trial.
Published in:
2017
By:
- Bloos, Frank;
- Rüddel, Hendrik;
- Thomas-Rüddel, Daniel;
- Schwarzkopf, Daniel;
- Pausch, Christine;
- Harbarth, Stephan;
- Schreiber, Torsten;
- Gründling, Matthias;
- Marshall, John;
- Simon, Philipp;
- Levy, Mitchell;
- Weiss, Manfred;
- Weyland, Andreas;
- Gerlach, Herwig;
- Schürholz, Tobias;
- Engel, Christoph;
- Matthäus-Krämer, Claudia;
- Scheer, Christian;
- Bach, Friedhelm;
- Riessen, Reimer
Publication type:
journal article
A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.701275
By:
- Mohammad, Shireen;
- Al Zoubi, Sura;
- Collotta, Debora;
- Krieg, Nadine;
- Wissuwa, Bianka;
- Ferreira Alves, Gustavo;
- Purvis, Gareth S. D.;
- Norata, Giuseppe Danilo;
- Baragetti, Andrea;
- Catapano, Alberico Luigi;
- Solito, Egle;
- Zechendorf, Elisabeth;
- Schürholz, Tobias;
- Correa-Vargas, Wilmar;
- Brandenburg, Klaus;
- Coldewey, Sina M.;
- Collino, Massimo;
- Yaqoob, Muhammad M.;
- Martin, Lukas;
- Thiemermann, Christoph
Publication type:
Article
Adverse effects of delayed antimicrobial treatment and surgical source control in adults with sepsis: results of a planned secondary analysis of a cluster-randomized controlled trial.
Published in:
2022
By:
- Rüddel, Hendrik;
- Thomas-Rüddel, Daniel O.;
- Reinhart, Konrad;
- Bach, Friedhelm;
- Gerlach, Herwig;
- Lindner, Matthias;
- Marshall, John C.;
- Simon, Philipp;
- Weiss, Manfred;
- Bloos, Frank;
- Schwarzkopf, Daniel;
- the MEDUSA study group;
- Marx, Gernot;
- Schindler, Achim;
- Schürholz, Tobias;
- Schlegel‑Höfner, Heike;
- Lehmann, Gunther;
- Sander, Annett;
- Friese, Steffen;
- Scholz, Christian
Publication type:
journal article
Efficacy and safety of early target-controlled plasma volume replacement with a balanced gelatine solution versus a balanced electrolyte solution in patients with severe sepsis/septic shock: study protocol, design, and rationale of a prospective, randomized, controlled, double-blind, multicentric, international clinical trial : GENIUS-Gelatine use in ICU and sepsis.
Published in:
2021
By:
- Marx, Gernot;
- Zacharowski, Kai;
- Ichai, Carole;
- Asehnoune, Karim;
- Černý, Vladimír;
- Dembinski, Rolf;
- Ferrer Roca, Ricard;
- Fries, Dietmar;
- Molnar, Zsolt;
- Rosenberger, Peter;
- Sanchez-Sanchez, Manuel;
- Schürholz, Tobias;
- Dehnhardt, Tamara;
- Schmier, Sonja;
- von Kleist, Elke;
- Brauer, Ute;
- Simon, Tim-Philipp
Publication type:
journal article
Welche Biomarker zu Diagnosestellung und Steuerung der antiinfektiven Therapie bei Sepsis?
Published in:
Anaesthesist, 2022, v. 71, n. 1, p. 3, doi. 10.1007/s00101-021-01067-7
By:
- Ehler, Johannes;
- Busjahn, Christoph;
- Schürholz, Tobias
Publication type:
Article
The Effect of Early Application of Synthetic Peptides 19-2.5 and 19-4LF to Improve Survival and Neurological Outcome in a Mouse Model of Cardiac Arrest and Resuscitation.
Published in:
Biomedicines, 2023, v. 11, n. 3, p. 855, doi. 10.3390/biomedicines11030855
By:
- Bajorat, Rika;
- Danckert, Lena;
- Ebert, Florian;
- Bancken, Theresa;
- Bergt, Stefan;
- Klawitter, Felix;
- Vollmar, Brigitte;
- Reuter, Daniel A.;
- Schürholz, Tobias;
- Ehler, Johannes
Publication type:
Article
Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature.
Published in:
2021
By:
- Thomas-Rüddel, Daniel O.;
- Hoffmann, Peter;
- Schwarzkopf, Daniel;
- Scheer, Christian;
- Bach, Friedhelm;
- Komann, Marcus;
- Gerlach, Herwig;
- Weiss, Manfred;
- Lindner, Matthias;
- Rüddel, Hendrik;
- Simon, Philipp;
- Kuhn, Sven-Olaf;
- Wetzker, Reinhard;
- Bauer, Michael;
- Reinhart, Konrad;
- Bloos, Frank;
- the MEDUSA study group;
- Marx, Gernot;
- Schindler, Achim;
- Schürholz, Tobias
Publication type:
journal article
Fever and hypothermia represent two populations of sepsis patients and are associated with outside temperature.
Published in:
Critical Care, 2021, v. 25, n. 1, p. 1, doi. 10.1186/s13054-021-03776-2
By:
- Thomas-Rüddel, Daniel O.;
- Hoffmann, Peter;
- Schwarzkopf, Daniel;
- Scheer, Christian;
- Bach, Friedhelm;
- Komann, Marcus;
- Gerlach, Herwig;
- Weiss, Manfred;
- Lindner, Matthias;
- Rüddel, Hendrik;
- Simon, Philipp;
- Kuhn, Sven-Olaf;
- Wetzker, Reinhard;
- Bauer, Michael;
- Reinhart, Konrad;
- Bloos, Frank;
- the MEDUSA study group;
- Marx, Gernot;
- Schindler, Achim;
- Schürholz, Tobias
Publication type:
Article
Teleintensivmedizin bei Sepsis - Zukunftsvision oder schon Realität?
Published in:
DIVI, 2023, v. 14, n. 4, p. 220, doi. 10.53180/DIVI.2023.0220-0225
By:
- Schürholz, Tobias;
- Dohmen, Sandra;
- Marx, Gernot
Publication type:
Article
Qualitätsindikatoren für die Intensivmedizin in Deutschland - ein Überblick.
Published in:
DIVI, 2022, v. 13, n. 3, p. 146, doi. 10.53180/DIVI.2022.0146-0151
By:
- Kumpf, Oliver;
- Bloos, Frank;
- Braun, Jan-Peter;
- Brinkmann, Alexander;
- Dubb, Rolf;
- Greim, Clemens;
- Kaltwasser, Arnold;
- Weimann, Jörg;
- Czorlich, Patrick;
- Riessen, Reimer;
- Sasse, Michael;
- Schürholz, Tobias;
- Waydhas, Christian;
- Wildenauer, René;
- Wöbker, Gabriele;
- Wrigge, Hermann;
- Marx, Gernot
Publication type:
Article
Potenzial telemedizinischer ICU-Hubs für die Gesundheitsversorgung in Europa.
Published in:
DIVI, 2022, v. 13, n. 3, p. 136, doi. 10.53180/DIVI.2022.0136-0142
By:
- Martin, Lukas;
- Meyer-Christodoulou, Janine;
- Peine, Arne;
- Wolfram, Thomas;
- Schürholz, Tobias;
- Marx, Gernot
Publication type:
Article
Tracheostomy in patients with acute respiratory distress syndrome is not related to quality of life, symptoms of psychiatric disorders or return-to-work: the prospective DACAPO cohort study.
Published in:
Annals of Intensive Care, 2020, v. 10, n. 1, p. 1, doi. 10.1186/s13613-020-00671-x
By:
- Blecha, Sebastian;
- Brandl, Magdalena;
- Zeman, Florian;
- Dodoo-Schittko, Frank;
- Brandstetter, Susanne;
- Karagiannidis, Christian;
- Bein, Thomas;
- Apfelbacher, Christian;
- for the DACAPO Study Group;
- Bickenbach, Johannes;
- Beeker, Thorben;
- Schürholz, Tobias;
- Pezechk, Jessica;
- Schloer, Jens;
- Jaschinski, Ulrich;
- Kummer, Ilse;
- Kuckein, Oliver;
- Weber-Carstens, Steffen;
- Goldmann, Anton;
- Angermair, Stefan
Publication type:
Article

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