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- Title
Transarterial Ethanol Ablation Combined with Transarterial Chemoembolization for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus.
- Authors
Biao Yang; Xin You; Min lan Yuan; Tian Qiang Qin; Lin Jia Duan; Jiao He; Ze Jun Fei; Xuan Zhou; Rui Yu Zan; Zheng Yin Liao
- Abstract
Background: The prognosis for hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT) is extremely poor. Objectives: This study aimed to evaluate the safety and effectiveness of transarterial ethanol ablation (TEA) for the treatment of HCC with PVTT. Methods: Patients were treated with TEA for PVTT under cone-beam-computed tomography and traditional transarterial chemoembolization (TACE) with epirubicin for intrahepatic lesions. Results: Seventeen men were successfully treated with TACE plus TEA. The mean overall survival was 18.3 ± 9.0 months (95% CI: 13.7 - 3.0 months). The quality of life (QoL) score increased from 56.9 ± 15.7 before the procedure to 88.5 ± 11.7 at 4 weeks after the procedure. Lipiodol accumulation grades of 3, 2, 1, and 0 were obtained in 3 (17.6%), 8 (47.1%), 6 (35.3%), and 0 (0%) patients, respectively. Conclusions: TEA is a safe and effective method for treating patients with PVTT, offering advantages for QoL, response rate after TEA, and OS.
- Subjects
CARDIOVASCULAR disease treatment; THROMBOSIS; HEPATOCELLULAR carcinoma; EPIRUBICIN; COMPUTED tomography; CONFIDENCE intervals; ETHANOL; LIVER blood-vessels; QUALITY of life; SURVIVAL; TREATMENT effectiveness; ABLATION techniques; DESCRIPTIVE statistics; CHEMOEMBOLIZATION; THERAPEUTICS
- Publication
Hepatitis Monthly, 2016, Vol 16, Issue 8, p1
- ISSN
1735-143X
- Publication type
Article
- DOI
10.5812/hepatmon.37584